DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8641 and Rasd1

DIOPT Version :9

Sequence 1:	NP_001261494.1	Gene:	CG8641 / 38771	FlyBaseID:	FBgn0035733	Length:	434	Species:	Drosophila melanogaster
Sequence 2:	NP_033052.1	Gene:	Rasd1 / 19416	MGIID:	1270848	Length:	280	Species:	Mus musculus

Alignment Length:	265	Identity:	132/265 - (49%)
Similarity:	173/265 - (65%)	Gaps:	27/265 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   159 SLPSAKNCYRLVMLGSSRAGKSSIVARFLGNRFEEAYTPTIEEFHRKLYRIRNEVFQLDILDTSG 223
            |:| ||||||:|:||||:.||::||:|||..|||:|||||||:||||.|.||.||:|||||||||
Mouse    18 SIP-AKNCYRMVILGSSKVGKTAIVSRFLTGRFEDAYTPTIEDFHRKFYSIRGEVYQLDILDTSG 81

  Fly   224 YHPFPAMRRLSFLTGDLFILVFSMDSRESFEEVVRLRENILETKWAALNPGSGFKKKSLPKIPMI 288
            .||||||||||.||||:||||||:|:|:|||||.||::.||:||....|     |.|....:|::
Mouse    82 NHPFPAMRRLSILTGDVFILVFSLDNRDSFEEVQRLKQQILDTKSCLKN-----KTKENVDVPLV 141

  Fly   289 LAGNKCDRDF-KTVQVDEVMGYIAGQDNCCTFVECSARQNYRIDDLFHSLFTVSNLPLEMTPNHH 352
            :.|||.|||| :.|:..|:...:......|.:.|.||::|..:|.:|.:||.::.||.||:|:.|
Mouse   142 ICGNKGDRDFYREVEQREIEQLVGDDPQRCAYFEISAKKNSSLDQMFRALFAMAKLPSEMSPDLH 206

  Fly   353 RRLVSVFGAP---------SPLPPHGSAVGGTKKNALSIKRRFSDACGVVTPNARRPSIRTDLNL 408
            |: |||....         ..|...||..||.          ..||.|::.|.|||||:.:||..
Mouse   207 RK-VSVQYCDVLHKKALRNKKLLRAGSGGGGD----------HGDAFGILAPFARRPSVHSDLMY 260

  Fly   409 MRSKT 413
            :|.||
Mouse   261 IREKT 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8641	NP_001261494.1	Rhes_like	167..434	CDD:133343	126/257 (49%)
CG8641	NP_001261494.1	RAS	167..338	CDD:214541	95/171 (56%)
Rasd1	NP_033052.1	Rhes_like	25..280	CDD:133343	126/257 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	190	1.000	Domainoid score	I3263
eggNOG	1	0.900	-	-		E2759_KOG0395
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H7509
Inparanoid	1	1.050	234	1.000	Inparanoid score	I3400
Isobase	1	0.950	-	0	Normalized mean entropy	S1908
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1398885at2759
OrthoFinder	1	1.000	-	-		FOG0005519
OrthoInspector	1	1.000	-	-		otm42396
orthoMCL	1	0.900	-	-		OOG6_107719
Panther	1	1.100	-	-	LDO	PTHR46149
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5615
SonicParanoid	1	1.000	-	-		X3937
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.810