Protein Alignment Mp and col15a1b

DIOPT Version :10

• Sequence 1: NP_001246651.1
• Gene: Mp / 38769
• FlyBaseID: FBgn0260660
• Length: 1039
• Species: Drosophila melanogaster
• Sequence 2: XP_009296788.1
• Gene: col15a1b / 558137
• ZFINID: ZDB-GENE-070912-689
• Length: 1315
• Species: Danio rerio
• Alignment Length: 1256
• Identity: 385/1256 - (30%)
• Similarity: 514/1256 - (40%)
• Gaps: 342/1256 - (27%)

  Fly    41 LTDIMNNNQFAGIEFGEAEDGFPAFRFLQTADVKSPYRMLLPEKLY-EFAILITFRQSSLKGGYL 104
            |||::.......:.|....:|:||:.|...|:|....:..:||..: :|||::|.:.||.:||.|
Zfish    93 LTDLVGMPLPPSVSFITGYEGYPAYSFGPHANVGRLTQSFVPEPFFTDFAIIVTVKPSSSRGGVL 157

  Fly   105 FSVVNPLDTVVQLGVHLSPVVKNSYNVSLVYTQADQNIGRKLASFGVAHVPDKWNSIALQVLSDK 169
            |::.:|..|:||||:.|:||...:..:.|.|::.......::|||.|..:..:|:...|.|...:
Zfish   158 FAITDPSQTIVQLGLALTPVEDQTQRIVLYYSEPRSANSAEVASFKVPDMTQQWSRFTLSVERQE 222

  Fly   170 VSFYYDCELRNTTLVTREPIELVFDSASTLYIGQAGSIIGGKFEGYLEKINVYGNPDAINVTCMP 234
            |..|.||:..:.....|....|.|...|.:::..|||....:|.|.::::.:           .|
Zfish   223 VRLYMDCDEYHIAPFKRSQQPLSFKPGSGIFVANAGSTGLERFVGSIQQLVI-----------KP 276

  Fly   235 PPKATIAPTTADDGSIFYEG--SGENILFEDSTEANILSDDFWNTGDEATDIFDASGMQPP---- 293
            .|:|.......||.|:...|  ||:.. ::|..|.....:.|..|.::...:...|.::.|
Zfish   277 DPRAAEEQCEEDDPSLQASGDRSGDGD-YDDEEEHARREETFGQTNNKEKTLRPTSPVEAPPIQS 340

  Fly   294 ---------GQTQYTHERPYRGI---------KGEKGERGPKGDSIRGPPGPPGPPGPK------ 334
                     |......||..||.         .|:|||||..|.:  ||||||||||..
Zfish   341 PDIEEGGFSGHVTPIDERLLRGTYKTDETGERVGQKGERGEPGPA--GPPGPPGPPGTSVPIRHS 403

  Fly   335 ---GETAPYPPFVETTSAGAKYTGECTCNASDILEAIKDNESLRESLRGAPGTPGKDGKPGTPGH 396
               |...|..|..:....|                        |....|.||:.|:|||||..|.
Zfish   404 GQPGPRGPQGPIGQPGGRG------------------------RPGKDGQPGSKGEDGKPGQRGQ 444

  Fly   397 TGATGVPGARGARGSEGAQG--------------------------------------------L 417
            ||..|:||..|.:|.:|..|                                            |
Zfish   445 TGPPGLPGESGVKGEKGDPGVGRTGLPGPPGPPGPPGPSKPVKVPYGFDALGSGFGDADIDTELL 509

  Fly   418 KGEPGVDGLPGVMGPPGP--------PGPPGLP--ENYD----------ESLMVNSMGAFRGTTQ 462
            :|.||..|.||:.|||||        |||||.|  :..|          :..:....|......:
Zfish   510 RGPPGPPGPPGIPGPPGPNSPLGGLLPGPPGAPGKDGRDGQSGLPGVPGQDGLPGQQGPKGAKGE 574

  Fly   463 PGAKGVPGEKGDAGQKGERGDPGHKGAHGPSGAKGEPGEP------------------------- 502
            .|.:|.||.||:.|..|:||.||..|..||.|..|.||.|
Zfish   575 HGIRGPPGPKGENGDPGQRGPPGPFGTMGPRGLPGPPGPPGPPGPINNNFMVDTLKDFEGSGESG 639

  Fly   503 ------------GTPGLPGLPGQVGQPG----------------------GLDGLASANGTKGEK 533
                        |.|||||.||..|.||                      ||.||..|.|.||:|
Zfish   640 SFLGTGILKGYQGPPGLPGPPGPQGPPGANGPPGLSVKGERGSPGPDGIHGLAGLPGARGPKGDK 704

  Fly   534 GEKGEKGMRGRRG--GTGATGPIGPPGK------------------------PGPMGDIGHSGR- 571
            |..||||.|||.|  .||..||.||||.                        |||||..|..||
Zfish   705 GNPGEKGERGRDGLNITGPPGPPGPPGPIINFQDLFLNDTAAKLNLTKIRGLPGPMGPEGLPGRA 769

  Fly   572 --PGMTGPKGEM------GPKGPKGDSG-----------------GREGLKGDKGDRGQDGRDGL 611
              ||..|||||:      ||.|.|||.|                 |..|.||.|||.|..|..|:
Zfish   770 GFPGPRGPKGEIGFPGVQGPPGLKGDKGEPGVSIAADGSIITSLRGPRGPKGTKGDIGLAGPHGI 834

  Fly   612 PGP---------------PGLPSTGGGDGDSGGVQYIPM--PGPPGPPGPPGL------------ 647
            |||               ||.|...|..||.|.... |.  |||||||||||.
Zfish   835 PGPIGPPGLKGGYGIPGRPGRPGIAGRKGDKGDASG-PSGPPGPPGPPGPPGRVIGLNGTVFPVP 898

  Fly   648 ---------------------------PGLS-------ISGPKGEPGVDSRSSFFGDASYYGRPG 678
                                       ||||       ..||||:.|.:.:....||....|.||
Zfish   899 PRPHCKTPVNNNNSQQGVKGEKGDEGNPGLSGTPVPHAYVGPKGDNGYNGQKGEKGDPGLPGPPG 963

  Fly   679 --ARSSLDELKALRELQDLRDRP--DGTAEPPRQPGHSHKHEETLGLVDGEEPYFSASSSNMNMK 739
              .|:.|...|.    :.:...|  .|...||..||:.....:......|.....|..||..::.
Zfish   964 LPGRTGLVGPKG----ESIVGPPGDTGAPGPPGLPGYGSPGPQGPPGAPGPPGTSSLYSSAASLP 1024

  Fly   740 IVPG-------------AVTFQNIDEMTKKSALNPPGTLAYITEEEALLVRVNKGWQYIALGTLV 791
            ..||             ..|::|...:.::|:....||:.|:.::..|.:||..||:.|.||.|:
Zfish  1025 GPPGPPGPPGAPGYGNPVSTYKNSQTLMRESSQAAEGTMGYVIDKSELYIRVRGGWKKIELGELI 1089

  Fly   792 PIATPAPPTTVA-----PSMRF--DLQSKNLLNSPP--PLLNTPTWYPRMLRVAALNEPSTGDLQ 847
            |:...:..:.::     ||.|.  .:.|:.|.:..|  .||...|.....|.:.|||.|.:||:.
Zfish  1090 PVPEDSSSSALSQGLSRPSDRSVPRVHSQELKSFLPGYNLLPDTTHSMPALHLVALNAPFSGDMH 1154

  Fly   848 GIRGADFACYRQGRRAGLLGTFKAFLSSRVQNLDTIVRPADR-DLPVVNTRGDVLFNSWKGIFNG 911
            ||||||:.||:|.|..||..|::|||||.:|:|.|||:.||| :|||||.:|:|||:||..:|:|
Zfish  1155 GIRGADYQCYQQARARGLTSTYRAFLSSHLQDLSTIVKKADRFNLPVVNLKGEVLFSSWMAMFSG 1219

  Fly   912 QGGFFSQAPRIYSFSGKNVMTDSTWPMKMVWHGSLPNGERSMDTYCDAWHSGDHLKGSFASNLDG 976
            .||.|.....||||.|:||:||..|..|:|||||...|.|....||:||.:||......||.|..
Zfish  1220 NGGVFDPLTPIYSFDGRNVLTDQAWSQKLVWHGSSTVGIRMTTNYCEAWRTGDMAVTGQASLLQT 1284

  Fly   977 HKLLEQKRQSCDSKLIILCVE 997
            .:||.|..:||.:..||||:|
Zfish  1285 GRLLGQHTRSCSNHFIILCIE 1305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mp	NP_001246651.1	LamG	58..222	CDD:473984	49/164 (30%)
		gly_rich_SclB	<292..>421	CDD:468478	49/203 (24%)
		gly_rich_SclB	<379..>616	CDD:468478	131/426 (31%)
		Collagen_trimer	744..792	CDD:466257	15/47 (32%)
		Endostatin-like	831..999	CDD:238151	86/168 (51%)
col15a1b	XP_009296788.1	LamG	99..278	CDD:473984	51/189 (27%)
		gly_rich_SclB	<368..>597	CDD:468478	71/254 (28%)
		gly_rich_SclB	<545..>799	CDD:468478	81/253 (32%)
		gly_rich_SclB	<741..>983	CDD:468478	71/246 (29%)
		Collagen_trimer	1042..1090	CDD:466257	15/47 (32%)
		Endostatin-like	1138..1307	CDD:238151	86/168 (51%)