DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment bin and FOXQ1

DIOPT Version :9

Sequence 1:NP_523950.2 Gene:bin / 38766 FlyBaseID:FBgn0045759 Length:676 Species:Drosophila melanogaster
Sequence 2:NP_150285.3 Gene:FOXQ1 / 94234 HGNCID:20951 Length:403 Species:Homo sapiens


Alignment Length:375 Identity:113/375 - (30%)
Similarity:150/375 - (40%) Gaps:79/375 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   221 HSPGGGYMSRISTSPSQVISNAHGMPVLNYSSSSSSPAKSLNGSESSPPSQNH----LENKVSGS 281
            :||..|..:|.:....:  .:|.|.|                |:|.:.|:...    .|...:|:
Human    49 NSPAAGGGARDTQGDGE--QSAGGGP----------------GAEEAIPAAAAAAVVAEGAEAGA 95

  Fly   282 AVVGTGGS-SQQDAPSTPDTTKKSGTRRPEKPALSYINMIGHAIKESPTGKLTLSEIYAYLQKSY 345
            |..|.||: |.:.|.|.|      .|||| ||..|||.:|..||::|..|:|||:||..||...:
Human    96 AGPGAGGAGSGEGARSKP------YTRRP-KPPYSYIALIAMAIRDSAGGRLTLAEINEYLMGKF 153

  Fly   346 EFFRGPYVGWKNSVRHNLSLNECFKKLPKGMGVGKP-GKGNYWTIDENSAHLFEDEGSLRRRPR- 408
            .||||.|.||:||||||||||:||.|:.:  ...:| ||.|||.::.||.:.|.|....|||.| 
Human   154 PFFRGSYTGWRNSVRHNLSLNDCFVKVLR--DPSRPWGKDNYWMLNPNSEYTFADGVFRRRRKRL 216

  Fly   409 GYRSKIKVKPYAG----HANGYYASGYGDAGMDNGNYYASPAFASYDYSAAGATGVSPAG--GQG 467
            .:|:.:   |..|    .|.|..|:.....        |:||.......|......||||  ...
Human   217 SHRAPV---PAPGLRPEEAPGLPAAPPPAP--------AAPASPRMRSPARQEERASPAGKFSSS 270

  Fly   468 FA------DPWNAHAAHSGSSSVGVGMGVGPLPQYTNISCL---------------AAGGNVNGS 511
            ||      .|:.:......:....:..|..|.|.......|               .||......
Human   271 FAIDSILRKPFRSRRLRDTAPGTTLQWGAAPCPPLPAFPALLPAAPCRALLPLCAYGAGEPARLG 335

  Fly   512 A-------TTPPLAHSALGMAPSASSSSSPLGAAATLQSDYAPTASLVAA 554
            |       |.|||..:.|..|..|.....|....|.|.......|:|.||
Human   336 AREAEVPPTAPPLLLAPLPAAAPAKPLRGPAAGGAHLYCPLRLPAALQAA 385

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
binNP_523950.2 Forkhead 311..399 CDD:278670 46/88 (52%)
FOXQ1NP_150285.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..75 8/43 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 94..116 9/27 (33%)
FH 119..197 CDD:238016 43/79 (54%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 216..266 13/60 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG2294
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
32.770

Return to query results.
Submit another query.