Protein Alignment bin and FOXN1

DIOPT Version :9

• Sequence 1: NP_523950.2
• Gene: bin / 38766
• FlyBaseID: FBgn0045759
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: XP_011523660.1
• Gene: FOXN1 / 8456
• HGNCID: 12765
• Length: 649
• Species: Homo sapiens
• Alignment Length: 725
• Identity: 154/725 - (21%)
• Similarity: 218/725 - (30%)
• Gaps: 278/725 - (38%)

  Fly    29 PPFSHPHAHSHPHQHTHTGHPYRAGNLLTGGNYQAMGGGESPTEL--IDEKPNIGYME------- 84
            ||.|...|...|.|              ..|:..| |.|..|..|  .|:.|..|:.|
Human    64 PPHSPRIASPGPEQ--------------VQGHCPA-GPGPGPFRLSPSDKYPGFGFEEAAASSPG 113

  Fly    85 --LK------------HYMDATPTATPVSAAQHYS------LSALHSMGTPPASSSPIPPYGVLM 129
              ||            .:.|..|.|....|.:.:|      |.|...:....|.:....| |...
Human   114 RFLKGSHAPFHPYKRPFHEDVFPEAETTLALKGHSFKTPGPLEAFEEIPVDVAEAEAFLP-GFSA 177

  Fly   130 TAHSAGSASPQSNSKTPTDLPQDLQYASSSTSTAKVQPLQVQ--------LQPLNHQYASTIKYC 186
            .|...|...|.....     ||.||     .|..||:|..::        ..||.|.|.|:
Human   178 EAWCNGLPYPSQEHG-----PQVLQ-----GSEVKVKPPVLESGAGMFCYQPPLQHMYCSS---- 228

  Fly   187 SNNTILSANDYQLLTSQEQAGQQQPQQLPAQQLQHSPGGGYMSRISTSPSQVISNAHGMPVLNYS 251
                                  |.|..      |:|||||      :.|...:.::|      |.
Human   229 ----------------------QPPFH------QYSPGGG------SYPIPYLGSSH------YQ 253

  Fly   252 SSSSSPAKSLNGSESSPPSQNHLENKVSGSAVVGTGGSSQQDAPSTPDTTKKSGTRRPEKPALSY 316
            ....:|..|.:|.:                             |..|            ||..||
Human   254 YQRMAPQASTDGHQ-----------------------------PLFP------------KPIYSY 277

  Fly   317 INMIGHAIKESPTGKLTLSEIYAYLQKSYEFFRGPYVGWKNSVRHNLSLNECFKKLPKGMGVGKP 381
            ..:|..|:|.|.||.|.:||||.::.:.:.:|:....|||||||||||||:||:|:....| ...
Human   278 SILIFMALKNSKTGSLPVSEIYNFMTEHFPYFKTAPDGWKNSVRHNLSLNKCFEKVENKSG-SSS 341

  Fly   382 GKGNYWTIDENSAHLFEDEGSL----RRRPRGYRSKIKVKPYAGHANGYYASGYGDAGMDNGNYY 442
            .||..|.:  |.|.:.:.:..|    |:.|...| |...||..      ..|..||.....|
Human   342 RKGCLWAL--NPAKIDKMQEELQKWKRKDPIAVR-KSMAKPEE------LDSLIGDKREKLG--- 394

  Fly   443 ASPAFASYDYSAAGATGVSP-AGGQGFADPWNAHAAHSGSSSVGVGMGVGPLPQYTNISCLAAGG 506
             ||.........:|:..:.| |...|.:.|  .|:.|...         ||:|....:..|..|.
Human   395 -SPLLGCPPPGLSGSGPIRPLAPPAGLSPP--LHSLHPAP---------GPIPGKNPLQDLLMGH 447

  Fly   507 NVNGSATTPPLAHSALGMAP--------------------SASSSSSPLGA------AATLQSDY 545
            ..:....|  ..|.:.|:||                    ..:...|||.|      :|.|.::.
Human   448 TPSCYGQT--YLHLSPGLAPPGPPQPLFPQPDGHLELRAQPGTPQDSPLPAHTPPSHSAKLLAEP 510

  Fly   546 APTASLVAAGYSYATSAGSLDNGLRSISLQQLPGLSSIQHAQAQAQAQAHHHHHQHHASHPSHSH 610
            :|..::    :......|.|...|.:|:    |.|:....
Human   511 SPARTM----HDTLLPDGDLGTDLDAIN----PSLTDFDF------------------------- 542

  Fly   611 QGHGSMHQ----------------NHGTSSTTPPPSQSGGSHGIDHSPIDRKPAYLPP--ISPPP 657
              .|::.:                :..|||:.|||..                   ||  ..|.|
Human   543 --QGNLWEQLKDDSLALDPLVLVTSSPTSSSMPPPQP-------------------PPHCFPPGP 586

  Fly   658 MMVALNGGGG 667
            .:.....|.|
Human   587 CLTETGSGAG 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bin	NP_523950.2	Forkhead	311..399	CDD:278670	38/87 (44%)
FOXN1	XP_011523660.1	Forkhead	272..359	CDD:278670	38/89 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810