Protein Alignment bin and FOXL2

DIOPT Version :10

• Sequence 1: NP_523950.2
• Gene: bin / 38766
• FlyBaseID: FBgn0045759
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: NP_075555.1
• Gene: FOXL2 / 668
• HGNCID: 1092
• Length: 376
• Species: Homo sapiens
• Alignment Length: 423
• Identity: 120/423 - (28%)
• Similarity: 167/423 - (39%)
• Gaps: 118/423 - (27%)

  Fly   259 KSLNGSESSPPSQNHLENKVSGSAVVGTGGSSQQDAPSTPDTTKKSGTRRPEKPALSYINMIGHA 323
            :::...|..|||        .|....|.||:    ||..||..        :||..||:.:|..|
Human    22 RTVKEPEGPPPS--------PGKGGGGGGGT----APEKPDPA--------QKPPYSYVALIAMA 66

  Fly   324 IKESPTGKLTLSEIYAYLQKSYEFFRGPYVGWKNSVRHNLSLNECFKKLPKGMGVGKPGKGNYWT 388
            |:||...:||||.||.|:...:.|:.....||:||:||||||||||.|:|:..|..:  ||||||
Human    67 IRESAEKRLTLSGIYQYIIAKFPFYEKNKKGWQNSIRHNLSLNECFIKVPREGGGER--KGNYWT 129

  Fly   389 IDENSAHLFEDEGSLRRRPRGYRSKIKVKPYAGH---ANGYYASGYGDAGMDNGNYYASPAFASY 450
            :|.....:|| :|:.|||   .|.|...:|...|   ..|.:.:|
Human   130 LDPACEDMFE-KGNYRRR---RRMKRPFRPPPAHFQPGKGLFGAG-------------------- 170

  Fly   451 DYSAAGATGVSPAG--GQGFADPWNAHAAHSGSSSVGVGMGVGPLPQYTNISCLAAGGNVNGSAT 513
              .|||..||:.||  |.|:..|                      |:|..      .|.:|.|..
Human   171 --GAAGGCGVAGAGADGYGYLAP----------------------PKYLQ------SGFLNNSWP 205

  Fly   514 TP----PLAHSALGMAPSASSSSSPLGAAATLQSDYAPTASLVAAGYSYATSAGSLDNGLRSISL 574
            .|    |:.:::..||.:|::::    |||......:|.|:.|..|  .|..|.|.....|..|:
Human   206 LPQPPSPMPYASCQMAAAAAAAA----AAAAAAGPGSPGAAAVVKG--LAGPAASYGPYTRVQSM 264

  Fly   575 QQLPGLSSIQH------AQAQAQAQAHHHHHQHH-----ASHPSHSHQGHGSMHQNHGTSSTTPP 628
            ...||:.:..:      |........|.|.|.||     |..|:..|.|           :..||
Human   265 ALPPGVVNSYNGLGGPPAAPPPPPHPHPHPHAHHLHAAAAPPPAPPHHG-----------AAAPP 318

  Fly   629 PSQSGGSHGIDHSPIDRKPAYLPPISPPPMMVA 661
            |.|...:     ||....|....|.|.|.:..|
Human   319 PGQLSPA-----SPATAAPPAPAPTSAPGLQFA 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bin	NP_523950.2	FH_FOX	312..391	CDD:469596	39/78 (50%)
FOXL2	NP_075555.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..53		12/50 (24%)
		FH_FOXL2	54..142	CDD:410802	43/90 (48%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	276..342		19/81 (23%)