DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bin and foxf1

DIOPT Version :9

Sequence 1:	NP_523950.2	Gene:	bin / 38766	FlyBaseID:	FBgn0045759	Length:	676	Species:	Drosophila melanogaster
Sequence 2:	NP_001073655.1	Gene:	foxf1 / 566407	ZFINID:	ZDB-GENE-050419-153	Length:	380	Species:	Danio rerio

Alignment Length:	473	Identity:	162/473 - (34%)
Similarity:	210/473 - (44%)	Gaps:	129/473 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   209 QQPQ-QLPAQQLQHSPGGGYMSRISTSPSQVISNAHGMPVLNYSSSSSS-PAKSLNGSESSPPSQ 271
            |||. |.||    ||      |.::..|.|.       ||:..|||||| .||..|
Zfish     6 QQPSVQTPA----HS------SPMTEKPVQT-------PVMETSSSSSSTKAKKTN--------- 44

  Fly   272 NHLENKVSGSAVVGTGGSSQQDAPSTPDTTKKSGTRRPEKPALSYINMIGHAIKESPTGKLTLSE 336
                                            :|.||||||..|||.:|..||:.|||.:|||||
Zfish    45 --------------------------------AGIRRPEKPPYSYIALIVMAIQSSPTKRLTLSE 77

  Fly   337 IYAYLQKSYEFFRGPYVGWKNSVRHNLSLNECFKKLPKGMGVGKPGKGNYWTIDENSAHLFEDEG 401
            ||.:||..:.||||.|.||||||||||||||||.|||||:  |:||||:|||||..|..:|| ||
Zfish    78 IYQFLQSRFPFFRGSYQGWKNSVRHNLSLNECFIKLPKGL--GRPGKGHYWTIDPASEFMFE-EG 139

  Fly   402 SLRRRPRGYRSKIK-VKPYAGHANGYYASGYGDAGMDNG---NYYASPAFASYDYSAAGATGVSP 462
            |.||||||:|.|.: :||          |.|   .|.||   |:...    ||::.
Zfish   140 SFRRRPRGFRRKCQALKP----------SMY---SMMNGLGFNHIPE----SYNFQ--------- 178

  Fly   463 AGGQGFADPWNAHAAHSG---------SSSVGVGMGVGPLPQYTNISCLAAGGNVNGSATTPPLA 518
            .||.|.:.|.|:.:..||         |:..|:|:....:|..:..|..:..|:..||:.|.
Zfish   179 GGGGGLSCPPNSLSLESGIGMMNGHLASNMEGMGLAGHSMPHLSTNSGHSYMGSCTGSSGTE--- 240

  Fly   519 HSALGMAPSASSSSSPLGAAATLQSDYAPTASLVAAGYSYATSAGSLDNGLRSISLQQL----PG 579
                  .|...||:|||..:..:...:|..:|..:|..|...:  ||:||...|..|.|    ||
Zfish   241 ------YPHHDSSASPLLTSGGVMDPHAVYSSTASAWPSAPPT--SLNNGTSYIKQQPLSPCNPG 297

  Fly   580 LSSIQHA---QAQAQAQAHHHHH---------QHHASHPSHSHQGHGSMHQNHGTSSTTPPPSQS 632
            .||:|.:   .:..|:..|.:.|         ::|...||...:.......|..|||:...|..|
Zfish   298 ASSLQPSLPTHSLEQSYLHQNGHGTTDLQGIPRYHTQSPSMCDRKEFVFSFNAMTSSSMHSPGSS 362

  Fly   633 GGSHGIDHSPIDRKPAYL 650
            ...|....|..|.||..:
Zfish   363 SYYHHQQVSYQDIKPCVM 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bin	NP_523950.2	Forkhead	311..399	CDD:278670	58/87 (67%)
foxf1	NP_001073655.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..49		23/100 (23%)
foxf1	NP_001073655.1	FH	52..140	CDD:214627	60/90 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	123	1.000	Domainoid score	I5529
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	199	1.000	Inparanoid score	I3759
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm25184
orthoMCL	1	0.900	-	-		OOG6_108542
Panther	1	1.100	-	-	O	PTHR46262
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5614
SonicParanoid	1	1.000	-	-		X1971
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.890