Protein Alignment bin and foxo4

DIOPT Version :10

• Sequence 1: NP_523950.2
• Gene: bin / 38766
• FlyBaseID: FBgn0045759
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: XP_009289443.1
• Gene: foxo4 / 563719
• ZFINID: ZDB-GENE-150311-1
• Length: 626
• Species: Danio rerio
• Alignment Length: 491
• Identity: 127/491 - (25%)
• Similarity: 191/491 - (38%)
• Gaps: 143/491 - (29%)

  Fly   254 SSSPAKSLNGSES---SPPSQNHLEN---------KVS---GSAVVGTGGSSQQDAPSTPDTTKK 303
            |:..|...:||||   :||::....:         |::   |..|.|.||:          |.:|
Zfish    32 SAVKAGGTDGSESAAGTPPAEEDKHDPQPIICDPEKIAVSEGGLVAGVGGA----------TPRK 86

  Fly   304 SGTRRPEKPALSYINMIGHAIKESPTGKLTLSEIYAYLQKSYEFFR-----GPYVGWKNSVRHNL 363
            ..:||......||.::|..||:.||..:|||::||.::.|:..:|:     ....|||||:||||
Zfish    87 GSSRRNAWGNQSYADLISQAIENSPEKRLTLAQIYDWMVKTVPYFKDKGDSNSSAGWKNSIRHNL 151

  Fly   364 SLNECFKKLPKGMGVGKPGKGNYWTIDENSAHLFEDEGSLRRRPRGYRSKIKVKPYAGHANGYYA 428
            ||:..|.::..    ...||.::|.::                |.|.::        |.|:...|
Zfish   152 SLHNKFLRVHN----ESTGKSSWWMLN----------------PEGGKT--------GKAHRRRA 188

  Fly   429 SGYGDAGMDN-GNYYASPAFASYDYSAAGATGVSPAGG--QGFADPWNAHAAHSGSSSVGVGMGV 490
            :     .||| |....|...|......|||.|:...||  ||           .|:|..|.....
Zfish   189 T-----SMDNSGKLLKSRIRAKQTKKQAGAAGIGGTGGGLQG-----------EGTSGTGNADSP 237

  Fly   491 GPLPQYTNISCLAAGGNVNGSATTPPLAHSALGMAPSASSSSSPLGA----AATLQSDY--APTA 549
            ||..|:......::..:..||...|.:..|   :.|..||::|.|..    .||.|.|.  .|..
Zfish   238 GPPGQFGKWGVNSSSPSSRGSLDDPDIWTS---IRPRTSSNASTLSGRLSPIATGQEDEDDLPED 299

  Fly   550 SLVAAGYSYATSAGSLDNGLRSISLQQL---PGLSSIQHAQAQAQ-AQAHHHHHQHHAS------ 604
            .|: .||    |:|:|.:.|....:::|   .||:.:...|..|. :.|.....|...|
Zfish   300 GLL-GGY----SSGNLPSTLPETLMEELDLIDGLTLMTAPQGGASPSMAPPAPPQPLPSASTLLP 359

  Fly   605 -----------HPSHSHQG------HGSMHQNHGTSSTTPP------------PSQSGGSHGIDH 640
                       .|:.:.||      ..|:..|.|:|:::|.            |..||.|   .|
Zfish   360 RGSSFPSFRQLQPTKASQGSTPPGPQSSVQPNAGSSTSSPSNFGNSLFSPLPGPGHSGFS---TH 421

  Fly   641 SPIDRKPAYLPPISPPP---MMVALN------GGGG 667
            .|...: |.|...||||   ||..::      ||||
Zfish   422 VPSSLE-ALLTSDSPPPSDVMMTQMDPLMPSQGGGG 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bin	NP_523950.2	FH_FOX	312..391	CDD:469596	29/83 (35%)
foxo4	XP_009289443.1	FH_FOXO4	91..176	CDD:410836	30/104 (29%)
		FOXO_KIX_bdg	375..>450	CDD:465228	21/78 (27%)
		FOXO-TAD	564..603	CDD:435506