DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bin and foxp4

DIOPT Version :9

Sequence 1:	NP_523950.2	Gene:	bin / 38766	FlyBaseID:	FBgn0045759	Length:	676	Species:	Drosophila melanogaster
Sequence 2:	XP_009304271.1	Gene:	foxp4 / 557245	ZFINID:	ZDB-GENE-101207-1	Length:	702	Species:	Danio rerio

Alignment Length:	552	Identity:	124/552 - (22%)
Similarity:	186/552 - (33%)	Gaps:	199/552 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   130 TAHSAGSASPQ---------SNS-KTP-TDLPQDLQYASSSTST---------AKVQPLQVQ--- 171
            |::||...|||         .|| .|| .|..:..::.||.|..         :|..|||..
Zfish   246 TSYSASKVSPQIPHHPLPNGQNSVHTPKRDRARLFEWISSFTKESSDEHLTPYSKGTPLQSTHST 310

  Fly   172 --------------------LQPLNHQYASTIKYCSNNTILSANDYQLLTSQEQAGQQQPQQLPA 216
                                .:.|.......||:.::...|....    |:|.:...|..|||..
Zfish   311 HEEHTASHPLYGHGECKWPGCEALCEDMGQFIKHLNSEHALDDRS----TAQCRVQMQVVQQLEI 371

  Fly   217 QQLQHSPG-GGYMSRISTSPSQVISNAHGMPVLNYSSSSSSPAKSLNGSESS---PPS------- 270
            |..:.|.. ...|:.:...||:   ..|....||.:||.|...:..:|....   ||:
Zfish   372 QLAKESERLQAMMAHLHMRPSE---PKHFNQPLNLASSVSLSKRENDGFPEGLPHPPTSAATPIT 433

  Fly   271 -QNHLENKVSGSAVVGTGGSSQQDAPS--TP---------DTTKKSGTRRPEKPALSYINMIGHA 323
             .....:.:|.|::.|.|...::::..  ||         :..|.:..|    |..:|.::|.||
Zfish   434 PMRQGPSVISSSSLHGVGPIRRRNSDKFCTPIASELAQNCEFYKNADVR----PPFTYASLIRHA 494

  Fly   324 IKESPTGKLTLSEIYAYLQKSYEFFRGPYVGWKNSVRHNLSLNECFKKLPKGMGVGKPGKGNYWT 388
            |.|:|..:|||:|||.:..:.:.:||.....|||:|||||||::||.::       :..||..||
Zfish   495 ILEAPDRQLTLNEIYNWFTRMFAYFRRNTATWKNAVRHNLSLHKCFVRV-------ENVKGAVWT 552

  Fly   389 IDENSAHLFEDEGSLRRRPRGYRSKIKVKPYAGHANGYYASGYGDAGMDNGNYYASPAFASYDYS 453
            :|       |.|...||.|:                   .:||.|       :..||.......|
Zfish   553 VD-------EVEYQKRRPPK-------------------MTGYVD-------FKGSPTLVKNMIS 584

  Fly   454 AAGATGVSPAGGQGFADPWNAHAAHSGSSSVGVGMGVGPLPQYTNISCLAAGGNVNGSATTPPLA 518
                                             |:|.|.|    |.|..||            ||
Zfish   585 ---------------------------------GLGFGSL----NASYQAA------------LA 600

  Fly   519 HSALGMAPSASSSSSPLGAAATL----QSDYAPTASLVAAGYSYATSAGSLDNGLRSISLQQLPG 579
            .|:||:..|.:..::..||:..:    ..|.:.|...|       .|.||..           ||
Zfish   601 ESSLGLLNSPTLMNNSTGASLNMLHIGHDDVSSTVEQV-------NSNGSCS-----------PG 647

  Fly   580 LSSIQHAQAQAQAQAHHHHHQHHASHPSHSHQ 611
            ||..|:.           |..|....|:...:
Zfish   648 LSPQQYG-----------HQIHVKEEPAEMEE 668

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bin	NP_523950.2	Forkhead	311..399	CDD:278670	33/87 (38%)
foxp4	XP_009304271.1	FOXP-CC	320..387	CDD:292777	13/70 (19%)
foxp4	XP_009304271.1	Forkhead	482..561	CDD:278670	36/96 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910