DRSC/TRiP Functional Genomics Resources

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Protein Alignment bin and foxc2

DIOPT Version :10

Sequence 1:NP_523950.2 Gene:bin / 38766 FlyBaseID:FBgn0045759 Length:676 Species:Drosophila melanogaster
Sequence 2:NP_998857.1 Gene:foxc2 / 407875 XenbaseID:XB-GENE-481382 Length:463 Species:Xenopus tropicalis


Alignment Length:445 Identity:117/445 - (26%)
Similarity:173/445 - (38%) Gaps:98/445 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   239 ISNAHGMPVLNY-SSSSSSPAKSLNGSESSPPS--QNHLENKVSGSAVVGTGGSSQQDAPSTPDT 300
            :::.:.:.|:.| |..:...|....||.::|.|  ..| |....|.|  .:.|......|:.|  
 Frog     7 VADPNALGVVPYLSEQNYYRAAGTYGSMATPMSVYPAH-EQYTPGMA--RSYGPYHHHQPAAP-- 66

  Fly   301 TKKSGTRRPEKPALSYINMIGHAIKESPTGKLTLSEIYAYLQKSYEFFRGPYVGWKNSVRHNLSL 365
                  :...||..|||.:|..||:.:|..|:||:.||.::...:.|:|....||:||:||||||
 Frog    67 ------KDLVKPPYSYIALITMAIQNAPDKKITLNGIYQFIMDRFPFYRENKQGWQNSIRHNLSL 125

  Fly   366 NECFKKLPKGMGVGKPGKGNYWTIDENSAHLFEDEGSLRRRPRGYRSKI------KVKPYAGHAN 424
            ||||.|:|:  ...|||||:|||:|.:|.::||:...||||.|..:..:      ::....|...
 Frog   126 NECFVKVPR--DDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDVSREKEDRILKDQGKVQ 188

  Fly   425 GYYASGYGDAGMDNGNYYASPAFASYDYSAAGATGV---SPAGGQGFADPWNAHAA--------- 477
            |...|      ::...:.......|........|.|   ||.||....|...:.|:         
 Frog   189 GPIPS------LELPKHDKKIVIKSESPELPVITKVENLSPDGGSAMQDSPRSVASTPSVSTENS 247

  Fly   478 ----HSGSSSVGVGMGVGPLPQYTNISCLAAGGNVNGSATTPPLAHSALGMAPSASSSSSPLGAA 538
                |..|:...|          .||..|..  :.:|..:..|......||.||           
 Frog   248 IPDQHPASNGFSV----------ENIMTLRT--SPHGDLSPVPAVPCRTGMVPS----------- 289

  Fly   539 ATLQSDYAPTASLVAAGYSYA-----TSAGSLDNGLRSISL------QQLPGLSSIQHAQAQAQA 592
              |..:|..|.|.|   ||.|     .::||....:|::||      ..:...|:::.|.:.   
 Frog   290 --LPINYTQTQSSV---YSQACTQSMDTSGSYQCSMRAMSLYTGDRPSHMCAPSTLEEATSD--- 346

  Fly   593 QAHHHHHQHHASHPSHSHQGHG-------SMHQNHGTSSTTPPPSQSGGSHGIDH 640
                 ||...||..:....|.|       |.||...|...|..|........|.|
 Frog   347 -----HHNGTASPLNSMSLGSGQESVLTSSHHQQTATGGQTAAPWYLNPGADISH 396

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
binNP_523950.2 FH_FOX 312..391 CDD:469596 39/78 (50%)
foxc2NP_998857.1 FH_FOXC1 66..158 CDD:410818 45/101 (45%)

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