Protein Alignment bin and Foxc1

DIOPT Version :10

• Sequence 1: NP_523950.2
• Gene: bin / 38766
• FlyBaseID: FBgn0045759
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: NP_599165.1
• Gene: Foxc1 / 364706
• RGDID: 1589718
• Length: 553
• Species: Rattus norvegicus
• Alignment Length: 514
• Identity: 140/514 - (27%)
• Similarity: 195/514 - (37%)
• Gaps: 161/514 - (31%)

  Fly   224 GGGYMSRISTSPSQVISN-AHGMPVLNYSSSSSSPAKSLNGSESSPPSQNHLENKVSGSAVVGTG 287
            ||||.:  ..:|..|.|: ||                    :|..|                  |
  Rat    34 GGGYTA--MPAPMSVYSHPAH--------------------AEQYP------------------G 58

  Fly   288 GSSQQDAPSTPDTTKKSGTRRPEKPALSYINMIGHAIKESPTGKLTLSEIYAYLQKSYEFFRGPY 352
            |.::...|.||....|...    ||..|||.:|..||:.:|..|:||:.||.::...:.|:|...
  Rat    59 GMARAYGPYTPQPQPKDMV----KPPYSYIALITMAIQNAPDKKITLNGIYQFIMDRFPFYRDNK 119

  Fly   353 VGWKNSVRHNLSLNECFKKLPKGMGVGKPGKGNYWTIDENSAHLFEDEGSLRRRPRGYRSKIKVK 417
            .||:||:||||||||||.|:|:  ...|||||:|||:|.:|.::||: ||..||.|.::.|..||
  Rat   120 QGWQNSIRHNLSLNECFVKVPR--DDKKPGKGSYWTLDPDSYNMFEN-GSFLRRRRRFKKKDAVK 181

  Fly   418 ---------------PYAGH----ANGYYASGYGD-----------------------------A 434
                           |.||.    |....|.|...                             |
  Rat   182 DKEEKGRLHLQEPPPPQAGRQPAPAPPEQAEGSAPGPQQPPVRIQDIKTENGTCPSPPQPLSPAA 246

  Fly   435 GMDNGNYYASPAFASYDYSAAG-ATGVSPAGGQGFADPWNAHAA-------------HSGSSSVG 485
            .:.:|:....|...|.|.|::. ::|.||.|....|.|.:..||             ||...||
  Rat   247 ALGSGSAATVPKIESPDSSSSSLSSGSSPPGSLPSARPLSLDAAEPAPPPQPAPPPHHSQGFSV- 310

  Fly   486 VGMGVGPLPQYTNISCLAAGGNVNGSATTPPLAHSALGMAPSASSSS-----SPLGAAATLQSDY 545
                       .|| ..:..|:..|||     |....|:..||::||     .||...|     |
  Rat   311 -----------DNI-MTSLRGSPQGSA-----AELGSGLLASAAASSRAGIAPPLALGA-----Y 353

  Fly   546 AP-TASLVAAGYSYATSAGSLDNGLRSISLQQLPGLSSIQHAQAQAQAQAHHHHHQHHASHPSHS 609
            :| .:||.::..|.::||||...|.....     |......|.....|..:|.:.|..:.:.:..
  Rat   354 SPGHSSLYSSPCSQSSSAGSSGGGGGGGG-----GGGGSSSAAGTGGAATYHCNLQAMSLYAAGE 413

  Fly   610 HQGHGSMHQNHGTSSTTPPPSQSGGSHGIDHSPIDRKPAY-LPPISPPPMMVALNGGGG 667
            ..||            ...|:..|||..:|    |..|.| |||.:........:||||
  Rat   414 RGGH------------LQGPAGGGGSAAVD----DPLPDYSLPPATSSSSSSLSHGGGG 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bin	NP_523950.2	FH_FOX	312..391	CDD:469596	39/78 (50%)
Foxc1	NP_599165.1	FH_FOXC1	73..165	CDD:410818	45/98 (46%)