Protein Alignment bin and FOXD4L4

DIOPT Version :10

• Sequence 1: NP_523950.2
• Gene: bin / 38766
• FlyBaseID: FBgn0045759
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: NP_954714.2
• Gene: FOXD4L4 / 349334
• HGNCID: 23762
• Length: 416
• Species: Homo sapiens
• Alignment Length: 405
• Identity: 97/405 - (23%)
• Similarity: 140/405 - (34%)
• Gaps: 150/405 - (37%)

  Fly   203 QEQAGQQQPQQ--LPAQQL----------QHSPGGGYMSRISTSPSQVISNAHGMPVLNYSSSSS 255
            :|:|.||..:|  .|..|:          :|..|||..|    .||:            :.:...
Human    43 EEEARQQFLEQSLQPGLQVARWGGVALPREHIEGGGGPS----DPSE------------FGTKFR 91

  Fly   256 SPAKSLNGSESSPPSQNHLENKVSGSAVVGTGGSSQQDAPSTPDTTKKSGTRRPEKPALSYINMI 320
            :|.:|...||.:                                       |:|.||..|||.:|
Human    92 APPRSAAASEDA---------------------------------------RQPAKPPYSYIALI 117

  Fly   321 GHAIKESPTGKLTLSEIYAYLQKSYEFFRGPYVGWKNSVRHNLSLNECFKKLPKGMGVGKPGKGN 385
            ..||.::|..:||||.|.|::...:.::|..:..|:||:|||||||:||.|:|:  ..|.|||||
Human   118 TMAILQNPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPR--EPGHPGKGN 180

  Fly   386 YWTIDENSAHLFEDEGSLRRRPRGYRSKIKVKPYAGHANGYYASGYGDAGMDN---GNYYASPA- 446
            ||::|..|..:|::...||||.|..|.::....:..|.   :......|.:.|   |....:||
Human   181 YWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAHLPHP---FPLPAAHAALHNPHPGPLLGAPAP 242

  Fly   447 ----FASYDYSAAG----------------------ATGVSPAGGQGFADP-------------- 471
                ..:|..:|.|                      |.....|.|...|.|
Human   243 PQPVPGAYPNTAPGRRPYALLHPHPLRYLLLSARVYAGAPKKAEGADLATPAPFPCCSPHLVLSL 307

  Fly   472 ------WNAHAAHSGSSSVGVGMGVGPLPQYTNISCLAAGGNVNGSATTPPLAHSALGMAPSASS 530
                  |..|.....|.|.            ..:.|..:|..|.|.....|
Human   308 GRRARVWRRHREADASLSA------------LRVLCKGSGERVQGLRRVCP-------------- 346

  Fly   531 SSSPLGAAATLQSDY 545
              .|.||.||..||:
Human   347 --RPRGATATCSSDH 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bin	NP_523950.2	FH_FOX	312..391	CDD:469596	37/78 (47%)
FOXD4L4	NP_954714.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..55		5/11 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	70..105		11/89 (12%)
		FH_FOXD4-like	108..203	CDD:410822	45/96 (47%)