Protein Alignment bin and foxa3

DIOPT Version :10

• Sequence 1: NP_523950.2
• Gene: bin / 38766
• FlyBaseID: FBgn0045759
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: NP_571374.1
• Gene: foxa3 / 30559
• ZFINID: ZDB-GENE-980526-423
• Length: 441
• Species: Danio rerio
• Alignment Length: 527
• Identity: 128/527 - (24%)
• Similarity: 205/527 - (38%)
• Gaps: 147/527 - (27%)

  Fly   176 NHQYASTIKYCSNNTILSANDYQLL-----TSQEQAGQQQPQQLPAQQLQHSP----GGGYMSRI 231
            |..|:|.   .:.|::.|.|.|..|     ||....|      .|:..|..||    ||| .:.:
Zfish    23 NEMYSSP---SAMNSVSSLNSYINLNSACSTSSMNMG------YPSAGLNSSPLSSMGGG-PNHM 77

  Fly   232 STSP----------SQVISNAHGMPVLNYSSSSSSPAKSLNGSESSPPSQNHLENKVSGSAVVGT 286
            |.||          :|:.|:|..:..|::..|...|...:  |..||.|.|..:
Zfish    78 SLSPVGSSLNPSSLTQLGSSASTLGPLSHYQSMGQPMSQI--SYPSPTSLNRTK----------- 129

  Fly   287 GGSSQQDAPSTPDTTKKSGTRRPEKPALSYINMIGHAIKESPTGKLTLSEIYAYLQKSYEFFRGP 351
                     ..|...::|.|.  .||..|||::|..||::|.:..|||:|||.::...:.::|..
Zfish   130 ---------EMPKPYRRSLTH--AKPPYSYISLITMAIQQSQSKMLTLNEIYQWIMDLFPYYREN 183

  Fly   352 YVGWKNSVRHNLSLNECFKKLPKGMGVGKPGKGNYWTIDENSAHLFEDEGSLRRRPRGYRSKIKV 416
            ...|:||:||:||.|:||.|:.:  ...|||||:||.:..||.::||:...|||:.|     .|:
Zfish   184 QQRWQNSIRHSLSFNDCFVKVAR--SPDKPGKGSYWALHPNSGNMFENGCYLRRQKR-----FKI 241

  Fly   417 KPYAGHANGYYASGYGDAGMDNGNYYASPAFASYDYSAAGATGVSPAGGQGFADPWNAHAAHSGS 481
            :..||..:   :|...|.....|.:.:......:          ||..|...|:..::.::|:||
Zfish   242 EEKAGKKS---SSKSQDGSSTKGTHSSEGMQEEH----------SPTTGSDGAESAHSDSSHAGS 293

  Fly   482 SSVGVGMGVGPLPQYTNISCLAAGGNVNGSATTPPLAHSALGMAPSASSSSSPLGAAATLQSDYA 546
            :|......:      ..:.|         .:..|.|.||:....||:.|:|.|
Zfish   294 TSEEQQRSL------VQLDC---------PSQAPNLLHSSPVPIPSSVSASMP------------ 331

  Fly   547 PTAS-LVAAGYSYATSAGSLDNGLRSISLQQLPGLSSIQHAQAQAQAQAHHHHHQHHASHPS--- 607
            |::| |.:.|  ...|...|.:.:..:.||..| |.|:.          .|.:..|..|..:
Zfish   332 PSSSHLHSQG--MGNSPHLLGSPMHHLDLQNDP-LKSMD----------PHFNFNHPFSITNLMS 383

  Fly   608 -------HSHQGHGSMHQNHGTSSTTPPPSQSGGSHGIDHSPIDRKPAYLPPISPPPMMVALNGG 665
                   .|:|.....:.::.||                 ||:..|..|   .:..|..:   ..
Zfish   384 NEQKMDLKSYQDQVMAYNSYATS-----------------SPVAAKQIY---DNAGPSAI---DS 425

  Fly   666 GGYYEGL 672
            |.||:.|
Zfish   426 GAYYQTL 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bin	NP_523950.2	FH_FOX	312..391	CDD:469596	33/78 (42%)
foxa3	NP_571374.1	Forkhead_N	17..142	CDD:369872	35/152 (23%)
		FH_FOXA3	141..242	CDD:410814	43/109 (39%)
		HNF_C	373..>408	CDD:430552	6/51 (12%)