Protein Alignment bin and FOXB1

DIOPT Version :10

• Sequence 1: NP_523950.2
• Gene: bin / 38766
• FlyBaseID: FBgn0045759
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: NP_036314.2
• Gene: FOXB1 / 27023
• HGNCID: 3799
• Length: 325
• Species: Homo sapiens
• Alignment Length: 328
• Identity: 88/328 - (26%)
• Similarity: 140/328 - (42%)
• Gaps: 70/328 - (21%)

  Fly   306 TRRPEKPALSYINMIGHAIKESPTGKLTLSEIYAYLQKSYEFFRGPYVGWKNSVRHNLSLNECFK 370
            |...:||..|||::...||:.||...|.|||||.::...:.::|.....|:||:|||||.|:||.
Human     8 TYSDQKPPYSYISLTAMAIQSSPEKMLPLSEIYKFIMDRFPYYRENTQRWQNSLRHNLSFNDCFI 72

  Fly   371 KLPKGMGVGKPGKGNYWTIDENSAHLFEDEGSLRRRPR---------------------GYRSKI 414
            |:|:  ...:||||::|.:..:...:||:...||||.|                     ..::|:
Human    73 KIPR--RPDQPGKGSFWALHPSCGDMFENGSFLRRRKRFKVLKSDHLAPSKPADAAQYLQQQAKL 135

  Fly   415 KVKPYAGHANGYY-----ASGYGDAGMDNGNYYASPAFASYDYSAAG--ATGVSPAGGQGFADPW 472
            ::...|  |:|.:     |:.|...|:      |.|:...:.::...  |......||..|:...
Human   136 RLSALA--ASGTHLPQMPAAAYNLGGV------AQPSGFKHPFAIENIIAREYKMPGGLAFSAMQ 192

  Fly   473 NAHAAH-------SGSSSVGVGM-----GVGPLPQYTNISCLAAGGNVNGSATTPPLAHSALGMA 525
            ...||:       :..||:|.|.     ..|.:...|.|| :|:|..........||.|:|....
Human   193 PVPAAYPLPNQLTTMGSSLGTGWPHVYGSAGMIDSATPIS-MASGDYSAYGVPLKPLCHAAGQTL 256

  Fly   526 PSASSSSSPLGAAA-----------TLQSD----YAPTASLVAAGYSY-ATSAGSLD---NGLRS 571
            |:......|..||.           ||.|:    .:||:|..|...|. ||.:.:|.   :.|.|
Human   257 PAIPVPIKPTPAAVPALPALPAPIPTLLSNSPPSLSPTSSQTATSQSSPATPSETLTSPASALHS 321

  Fly   572 ISL 574
            :::
Human   322 VAV 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bin	NP_523950.2	FH_FOX	312..391	CDD:469596	33/78 (42%)
FOXB1	NP_036314.2	FH_FOXB2	1..110	CDD:410817	42/103 (41%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	284..325		11/41 (27%)