Protein Alignment bin and FOXD3

DIOPT Version :10

• Sequence 1: NP_523950.2
• Gene: bin / 38766
• FlyBaseID: FBgn0045759
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: NP_036315.1
• Gene: FOXD3 / 27022
• HGNCID: 3804
• Length: 478
• Species: Homo sapiens
• Alignment Length: 454
• Identity: 127/454 - (27%)
• Similarity: 183/454 - (40%)
• Gaps: 80/454 - (17%)

  Fly   187 SNNTILSANDYQ----------LLTSQEQAGQQQPQQLPAQQLQHSPGGGYMSRISTSPSQVISN 241
            |..|:|:|.|..          |......||...|...|..:|..:.        ...|:   :.
Human    13 SGQTVLTAEDVDIDVVGEGDDGLEEKDSDAGCDSPAGPPELRLDEAD--------EVPPA---AP 66

  Fly   242 AHGMPVLNYSSSSSSPAKSLN-----GSESSPPSQNHLENKVSGSAVVGTG-------GSSQQDA 294
            .||.|...:....:.|.::..     |.:...|..:..:..|.|.....:|       ||:...|
Human    67 HHGQPQPPHQQPLTLPKEAAGAGAGPGGDVGAPEADGCKGGVGGEEGGASGGGPGAGSGSAGGLA 131

  Fly   295 PSTPDTTKKSGTRRPEKPALSYINMIGHAIKESPTGKLTLSEIYAYLQKSYEFFRGPYVGWKNSV 359
            ||.|..:.       .||..|||.:|..||.:||..|||||.|..::...:.::|..:..|:||:
Human   132 PSKPKNSL-------VKPPYSYIALITMAILQSPQKKLTLSGICEFISNRFPYYREKFPAWQNSI 189

  Fly   360 RHNLSLNECFKKLPKGMGVGKPGKGNYWTIDENSAHLFEDEGSLRRRPRGYR---------SKIK 415
            |||||||:||.|:|:  ..|.||||||||:|..|..:|::...||||.|..|         :.:.
Human   190 RHNLSLNDCFVKIPR--EPGNPGKGNYWTLDPQSEDMFDNGSFLRRRKRFKRHQQEHLREQTALM 252

  Fly   416 VKPYAGHANGYYASGYGDAGMDNGNYYASPAFA--SYDYSAAGATGVSPAGGQ-GFADPWNA--- 474
            ::.:..::   .|:..|.||.....|...||.|  :|.:.||.|...:.|..| .:|.|..|
Human   253 MQSFGAYS---LAAAAGAAGPYGRPYGLHPAAAAGAYSHPAAAAAAAAAAALQYPYALPPVAPVL 314

  Fly   475 -------HAAHSGSSSVGVGMGVGP-LPQYTNI--SCLAAGGNVNGSATTPPLAHSALGMAPSAS 529
                   .:...|..:...|..:|| |....|.  :..||.|....:.||..|..|.....||.|
Human   315 PPAVPLLPSGELGRKAAAFGSQLGPGLQLQLNSLGAAAAAAGTAGAAGTTASLIKSEPSARPSFS 379

  Fly   530 SSSSPLGAAATLQSDYAPTASLVAAGYSYATSAGSLDNGLRSISLQQLPGLSSIQHAQAQAQAQ 593
            ..:...|..|      ||..|.|.||.:..|  |....|..:.|..:.||  ::|.|...|..|
Human   380 IENIIGGGPA------APGGSAVGAGVAGGT--GGSGGGSTAQSFLRPPG--TVQSAALMATHQ 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bin	NP_523950.2	FH_FOX	312..391	CDD:469596	39/78 (50%)
FOXD3	NP_036315.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..136		26/133 (20%)
		FH_FOXD3	140..236	CDD:410821	47/97 (48%)