Protein Alignment bin and Foxa2

DIOPT Version :10

• Sequence 1: NP_523950.2
• Gene: bin / 38766
• FlyBaseID: FBgn0045759
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: NP_001386014.1
• Gene: Foxa2 / 25099
• RGDID: 2808
• Length: 465
• Species: Rattus norvegicus
• Alignment Length: 458
• Identity: 128/458 - (27%)
• Similarity: 184/458 - (40%)
• Gaps: 102/458 - (22%)

  Fly   222 SPGGGYMSRISTSPSQVISNAHGMPVLN-YSSSSSSP-----AKSLNGSESSPPSQNHLENKVSG 280
            |||.|.|:.:|.|     :.|.|:..:. :.|.|.||     |.::.|  .:|     ..|..|.
  Rat    87 SPGAGAMAGMSGS-----AGAAGVAGMGPHLSPSLSPLGGQAAGAMGG--LAP-----YANMNSM 139

  Fly   281 SAVVGTGGSSQQDAPSTPDTTKKSGTRRPEKPALSYINMIGHAIKESPTGKLTLSEIYAYLQKSY 345
            |.:.|..|.|:   ...|.|.::|.|.  .||..|||::|..||::||...|||||||.::...:
  Rat   140 SPMYGQAGLSR---ARDPKTYRRSYTH--AKPPYSYISLITMAIQQSPNKMLTLSEIYQWIMDLF 199

  Fly   346 EFFRGPYVGWKNSVRHNLSLNECFKKLPKGMGVGKPGKGNYWTIDENSAHLFEDEGSLRRRPR-G 409
            .|:|.....|:||:||:||.|:||.|:|:  ...|||||::||:..:|.::||:...|||:.| .
  Rat   200 PFYRQNQQRWQNSIRHSLSFNDCFLKVPR--SPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFK 262

  Fly   410 YRSKIKVKPYAGHANGYYASGYGDAGMDNGNYYASPAFASYDY--SAAGATGVSPAGGQGFADPW 472
            ...::.:|..||            ||...|...|....||...  .|||:...:|||
  Rat   263 CEKQLALKEAAG------------AGSGGGKKTAPGTQASQVQLGEAAGSASETPAG-------- 307

  Fly   473 NAHAAHSGSSSVGVGMGVGPLPQYTNISCLAAGG-----NVNGSATTPPLAHSALGMAPSASSSS 532
             ..:.||.:|         |..::..      ||     ....||.:||        .|:.|...
  Rat   308 -TESPHSSAS---------PCQEHKR------GGLSELKGTPASALSPP--------EPAPSPGQ 348

  Fly   533 SPLGAAATLQSDY---APTASLVAAGYSYATSAGSLDNGLRSISLQQLPGLSSIQHAQAQAQAQA 594
            ....||..|...:   .|..:.:...:.||.:.....|.|.|                   ..|.
  Rat   349 QQQAAAHLLVPPHHPGLPPEAHLKPEHHYAFNHPFSINNLMS-------------------SEQQ 394

  Fly   595 HHHHHQHHASHPSHSHQGHGSMHQNHGTSSTTPPPSQSG---GSHGIDHSPIDRKPAYLPPISPP 656
            |||.|.||..|..........||...|..|..|.....|   ...|:|.||:....:|...:...
  Rat   395 HHHSHHHHQPHKMDLKTYEQVMHYPGGYGSPMPGSLAMGPVTNKAGLDASPLAADTSYYQGVYSR 459

  Fly   657 PMM 659
            |:|
  Rat   460 PIM 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bin	NP_523950.2	FH_FOX	312..391	CDD:469596	37/78 (47%)
Foxa2	NP_001386014.1	Forkhead_N	23..164	CDD:369872	26/93 (28%)
		FH_FOXA2	163..264	CDD:410813	45/104 (43%)
		COG5025	<164..380	CDD:227358	78/261 (30%)
		HNF_C	380..454	CDD:430552	22/92 (24%)