DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bin and Foxi3

DIOPT Version :9

Sequence 1:	NP_523950.2	Gene:	bin / 38766	FlyBaseID:	FBgn0045759	Length:	676	Species:	Drosophila melanogaster
Sequence 2:	NP_001094934.1	Gene:	Foxi3 / 232077	MGIID:	3511278	Length:	399	Species:	Mus musculus

Alignment Length:	427	Identity:	109/427 - (25%)
Similarity:	162/427 - (37%)	Gaps:	130/427 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   185 YCSNNTILSANDYQLLTSQEQAGQQQPQQLP-AQQLQHSPGGGYMSRISTSPSQVIS-----NAH 243
            ||.:|.:.|                ||...| |.....:|.|  :|..:..|:...:     |..
Mouse     4 YCGDNFVYS----------------QPAAAPGAPPTSRAPYG--LSDYAAPPAAAANPYLWLNGP 50

  Fly   244 GM----PVLNYSSSSSSPAKSLNGSESSPPSQNHLENKVSGSAVVGTGGSSQQ-------DAPST 297
            |:    ...:|..:...|..:..|....||            |..||...:|:       .||::
Mouse    51 GVGGPASAASYLGAPPPPPGAAPGPFLQPP------------AAPGTFAGAQRGFAQPSASAPAS 103

  Fly   298 PDTTKKSGTRRP-----------------EKPALSYINMIGHAIKESPTGKLTLSEIYAYLQKSY 345
            |     :|:..|                 .:|..||..:|..||:.:|..|||||.||.::..::
Mouse   104 P-----AGSAAPGELGWLSMASREDLMKMVRPPYSYSALIAMAIQSAPERKLTLSHIYQFVADNF 163

  Fly   346 EFFRGPYVGWKNSVRHNLSLNECFKKLPKGMGVGKPGKGNYWTIDENSAHLFEDEGSLRRRPR-- 408
            .|::....||:||:|||||||:||||:|:  ....||||||||:|.|...:| |.|:.||:.|
Mouse   164 PFYQRSKAGWQNSIRHNLSLNDCFKKVPR--DEDDPGKGNYWTLDPNCEKMF-DNGNFRRKRRRR 225

  Fly   409 -----------------GYRSKIKVKPYAGHANGYYASGYGDAGMDNGNYYASPAFASYDYSAAG 456
                             |..|:::|   :|...|           |:.:....|:.:........
Mouse   226 AEASSNLTVPSGTSKSEGQSSRLRV---SGKLEG-----------DSPSSILRPSQSPEPPEGTK 276

  Fly   457 ATGVSPAGG--------QGFADPWNAHAAHSGSSSVGVGMGVGPLPQYTNISCLAAGGNVNGSAT 513
            :|..||...        ..|...:|....:| |||:|   ....||.    |....||....|:|
Mouse   277 STASSPGASTLTSTPCLNTFLSTFNTLNVNS-SSSMG---NQRTLPG----SRRHLGGTQLPSST 333

  Fly   514 TPPLAHSALGMAPSASSSS---SPLGAAATLQSDYAP 547
            .|..:      .|.:|..|   |.:|.:..|.|.|.|
Mouse   334 FPNTS------VPDSSPDSMQLSTVGGSNQLSSYYNP 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bin	NP_523950.2	Forkhead	311..399	CDD:278670	42/87 (48%)
Foxi3	NP_001094934.1	Forkhead	129..215	CDD:278670	42/88 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910