Protein Alignment bin and FOXD2

DIOPT Version :9

• Sequence 1: NP_523950.2
• Gene: bin / 38766
• FlyBaseID: FBgn0045759
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: NP_004465.3
• Gene: FOXD2 / 2306
• HGNCID: 3803
• Length: 495
• Species: Homo sapiens
• Alignment Length: 448
• Identity: 128/448 - (28%)
• Similarity: 180/448 - (40%)
• Gaps: 69/448 - (15%)

  Fly   224 GGGYMSRIS--TSPSQVISNAHGMPVLNYSSSSSSPAKSLNGSESSPPSQNHLENKVSGSAVVGT 286
            |||.:...|  .:|..|:.:.|..|.....:..:...:...|.....|.........:.:...|.
Human    35 GGGELPARSGPRAPRDVLPHGHEPPAEEAEADLAEDEEESGGCSDGEPRALASRGAAAAAGSPGP 99

  Fly   287 GGSSQQDA--PSTPDTTKKSGTRRP-EKPALSYINMIGHAIKESPTGKLTLSEIYAYLQKSYEFF 348
            |.::.:.|  |.....:..:.||.| .||..|||.:|..||.:||..:||||||..::...:.::
Human   100 GAAAARGAAGPGPGPPSGGAATRSPLVKPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYY 164

  Fly   349 RGPYVGWKNSVRHNLSLNECFKKLPKGMGVGKPGKGNYWTIDENSAHLFEDEGSLRRRPRGYRSK 413
            |..:..|:||:|||||||:||.|:|:  ..|.||||||||:|..||.:|::...||||.|..|..
Human   165 REKFPAWQNSIRHNLSLNDCFVKIPR--EPGNPGKGNYWTLDPESADMFDNGSFLRRRKRFKRQP 227

  Fly   414 IKVKPYA---GHANGYYASGYGDAGMDNGNYYASPAFASYDYSAAG------ATGVSPAGGQGFA 469
            :. .|:.   .|.......|...|| |.|.:.  |.||:|.....|      |.|..|.|.....
Human   228 LP-PPHPHPHPHPELLLRGGAAAAG-DPGAFL--PGFAAYGAYGYGYGLALPAYGAPPPGPAPHP 288

  Fly   470 DPWN---AHAAHSGSS----SVGVGMGVGPLPQYTNISCLAAGGNVNGSATTP-PLAHSALGMAP 526
            .|..   |.||.:.::    ||..|....|.|.....|..|..    |||..| |.:.|..|..|
Human   289 HPHPHAFAFAAAAAAAPCQLSVPPGRAAAPPPGPPTASVFAGA----GSAPAPAPASGSGPGPGP 349

  Fly   527 SASSS--SSPLGAAATLQSDYAPTASLVAAGYSYATSAGSLDNGLRS----------ISLQQLPG 579
            :...:  .:.||.|   ::.||.:.|..|||.:.......|..||::          ....|.|.
Human   350 AGLPAFLGAELGCA---KAFYAASLSPPAAGTAAGLPTALLRQGLKTDAGGGAGGGGAGAGQRPS 411

  Fly   580 LSSIQHAQAQAQAQAHHHHHQHHASHPSHSHQGHGSMHQNHGTSSTTPPPSQSGGSHG 637
            . ||.|..                     .|.|.|:.....|..|..||.:.:.|..|
Human   412 F-SIDHIM---------------------GHGGGGAAPPGAGEGSPGPPFAAAAGPGG 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bin	NP_523950.2	Forkhead	311..399	CDD:278670	44/87 (51%)
FOXD2	NP_004465.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	14..122		14/86 (16%)
		Forkhead	127..213	CDD:278670	44/87 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	312..347		11/38 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	397..444		12/68 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900