Protein Alignment bin and FOXE3

DIOPT Version :10

• Sequence 1: NP_523950.2
• Gene: bin / 38766
• FlyBaseID: FBgn0045759
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: NP_036318.1
• Gene: FOXE3 / 2301
• HGNCID: 3808
• Length: 319
• Species: Homo sapiens
• Alignment Length: 344
• Identity: 102/344 - (29%)
• Similarity: 150/344 - (43%)
• Gaps: 72/344 - (20%)

  Fly   244 GMPVLNYSSSSSSPAKSLNGSESSPPSQNHLENKVSGSAVVGTGGSSQQDAPSTPDTTKKSGTRR 308
            |.|.|...:.|..|...|.|:|   |.:...|      |..|.|.::...||. |...:    ||
Human    15 GFPALPAVAPSGPPPSPLAGAE---PGREPEE------AAAGRGEAAPTPAPG-PGRRR----RR 65

  Fly   309 P---EKPALSYINMIGHAIKESPTGKLTLSEIYAYLQKSYEFFRGPYVGWKNSVRHNLSLNECFK 370
            |   .||..|||.:|..|:..:|..:|||:.||.::.:.:.|:|.....|:||:||||:||:||.
Human    66 PLQRGKPPYSYIALIAMALAHAPGRRLTLAAIYRFITERFAFYRDSPRKWQNSIRHNLTLNDCFV 130

  Fly   371 KLPKGMGVGKPGKGNYWTIDENSAHLFEDEGSLRRRPRGYRSKIKVKPYAGHANGYYASGYGDAG 435
            |:|:  ..|.||||||||:|..:|.:|::...||||.|..|:::     ..||
Human   131 KVPR--EPGNPGKGNYWTLDPAAADMFDNGSFLRRRKRFKRAEL-----PAHA------------ 176

  Fly   436 MDNGNYYASPA------FASYDYSAAGATGVS-----PAGGQGFADPWNAHAAHSGSSSVGV--- 486
                  .|:|.      :|.|    |.|.|.:     |:.|.|.:.|   ....|..|.|.:
Human   177 ------AAAPGPPLPFPYAPY----APAPGPALLVPPPSAGPGPSPP---ARLFSVDSLVNLQPE 228

  Fly   487 --GMGVGPLPQYTNISCLAAGGNVNGSATTPPLAHSALG---MAPSASSSSSPLGAAATLQSDYA 546
              |:|....|........||......:|.:||| :|.:.   :.|:......|| .|..|.:...
Human   229 LAGLGAPEPPCCAAPDAAAAAFPPCAAAASPPL-YSQVPDRLVLPATRPGPGPL-PAEPLLALAG 291

  Fly   547 PTASL--VAAGYSYATSAG 563
            |.|:|  ::.|.:|....|
Human   292 PAAALGPLSPGEAYLRQPG 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bin	NP_523950.2	FH_FOX	312..391	CDD:469596	36/78 (46%)
FOXE3	NP_036318.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..69		19/67 (28%)
		FH_FOX	71..159	CDD:469596	40/89 (45%)