DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bin and FOXI1

DIOPT Version :9

Sequence 1:	NP_523950.2	Gene:	bin / 38766	FlyBaseID:	FBgn0045759	Length:	676	Species:	Drosophila melanogaster
Sequence 2:	NP_036320.2	Gene:	FOXI1 / 2299	HGNCID:	3815	Length:	378	Species:	Homo sapiens

Alignment Length:	382	Identity:	104/382 - (27%)
Similarity:	152/382 - (39%)	Gaps:	99/382 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   211 PQQLPAQQLQHSPGGGYMSRISTSPSQVISNAHGMPVLNYSSSSSSPAKSLNGSESSP--PSQNH 273
            ||.:|:.|.....|||   ....:|:         |.|.::..:.:|...|.|..:||  |....
Human    38 PQGVPSPQRPSFEGGG---EYGATPN---------PYLWFNGPTMTPPPYLPGPNASPFLPQAYG 90

  Fly   274 LENKVSGSAVVGTGGS--SQQDAPSTPDTTKKSGTRRPEKPALSYINMIGHAIKESPTGKLTLSE 336
            ::..:..| |.|.|||  .....||..:..|.      .:|..||..:|..||..:|..:||||:
Human    91 VQRPLLPS-VSGLGGSDLGWLPIPSQEELMKL------VRPPYSYSALIAMAIHGAPDKRLTLSQ 148

  Fly   337 IYAYLQKSYEFFRGPYVGWKNSVRHNLSLNECFKKLPKGMGVGKPGKGNYWTIDENSAHLFEDEG 401
            ||.|:..::.|:.....||:||:|||||||:||||:|:  ....||||||||:|.|...:| |.|
Human   149 IYQYVADNFPFYNKSKAGWQNSIRHNLSLNDCFKKVPR--DEDDPGKGNYWTLDPNCEKMF-DNG 210

  Fly   402 SLRRRPRGYRSKIKVKPYAGHANGYYASGYGDAGMDNGNYYASPAFASYDYSAAGATGVSPAGGQ 466
            :.||: |..:|                                      |.|::.|
Human   211 NFRRK-RKRKS--------------------------------------DVSSSTA--------- 227

  Fly   467 GFADPWNAHAAHSGSSSVGVGMGVGPLPQYTNISCLAAGGNVNGSATTPPLAHSALGMAPSASSS 531
                   :.|.....||:.|..     |:.|....:..|.:..|:.::|.       ..||...|
Human   228 -------SLALEKTESSLPVDS-----PKTTEPQDILDGASPGGTTSSPE-------KRPSPPPS 273

  Fly   532 SSP-----LGAAATLQSDYAPTA-SLVAAGYSYATSAGSLDNGLRSISLQQLPGLSS 582
            .:|     |.:.....|..:||: .||..|.|...|..:..|.|...|...|..||:
Human   274 GAPCLNSFLSSMTAYVSGGSPTSHPLVTPGLSPEPSDKTGQNSLTFNSFSPLTNLSN 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bin	NP_523950.2	Forkhead	311..399	CDD:278670	42/87 (48%)
FOXI1	NP_036320.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26
		FH	123..211	CDD:214627	43/90 (48%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	208..278		22/136 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810