Protein Alignment bin and FOXD1

DIOPT Version :10

• Sequence 1: NP_523950.2
• Gene: bin / 38766
• FlyBaseID: FBgn0045759
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: NP_004463.1
• Gene: FOXD1 / 2297
• HGNCID: 3802
• Length: 465
• Species: Homo sapiens
• Alignment Length: 401
• Identity: 125/401 - (31%)
• Similarity: 159/401 - (39%)
• Gaps: 96/401 - (23%)

  Fly   258 AKSLNGSESSP---PSQNHLENKVSGSAVVGTGGSSQQDAPSTPDTTKKSGTRRP-EKPALSYIN 318
            |....||.:.|   |:.........|....|.|||:            .||.:.| .||..|||.
Human    80 APPAGGSPAPPGPAPAAGAGAGGGGGGGGAGGGGSA------------GSGAKNPLVKPPYSYIA 132

  Fly   319 MIGHAIKESPTGKLTLSEIYAYLQKSYEFFRGPYVGWKNSVRHNLSLNECFKKLPKGMGVGKPGK 383
            :|..||.:||..:||||||..::...:.::|..:..|:||:|||||||:||.|:|:  ..|.|||
Human   133 LITMAILQSPKKRLTLSEICEFISGRFPYYREKFPAWQNSIRHNLSLNDCFVKIPR--EPGNPGK 195

  Fly   384 GNYWTIDENSAHLFEDEGSLRRRPRGYRSKIKVKPYAGHANGYYASGYGDAGMDNGNYYASPAFA 448
            |||||:|..||.:|::...||||.|..|..: :.|.|..|......|.|
Human   196 GNYWTLDPESADMFDNGSFLRRRKRFKRQPL-LPPNAAAAESLLLRGAG---------------- 243

  Fly   449 SYDYSAAGATGVSPAGGQGF--ADPWNAHAAHSGSSSVGVGMGVGPLPQYTNISCLAAGGNVNGS 511
                 |||..|...|....|  |.|...||...|....|.|:   .||.|...|.|.|......:
Human   244 -----AAGGAGDPAAAAALFPPAPPPPPHAYGYGPYGCGYGL---QLPPYAPPSALFAAAAAAAA 300

  Fly   512 AT-----TPP-----------LAHSALGMAPSASSSSSPLGAAATLQSDYAP-TASLVAAGYSYA 559
            |.     :||           ||.:|.|..|      .|||||..     .| .||...||...|
Human   301 AAAFHPHSPPPPPPPHGAAAELARTAFGYRP------HPLGAALP-----GPLPASAAKAGGPGA 354

  Fly   560 TSAGSLDNGLRSISLQQL-PGLSSIQHAQAQAQAQAHHHHHQHHASHPSHSHQGHGSMHQNHGTS 623
            ::.......:.||....| |..::...|||.|.|||          .||.|            ..
Human   355 SALARSPFSIESIIGGSLGPAAAAAAAAQAAAAAQA----------SPSPS------------PV 397

  Fly   624 STTPPPSQSGG 634
            :..|.|..|||
Human   398 AAPPAPGSSGG 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bin	NP_523950.2	FH_FOX	312..391	CDD:469596	39/78 (50%)
FOXD1	NP_004463.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..117		10/48 (21%)
		FH_FOXD1_D2-like	125..223	CDD:410820	49/99 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	391..410		8/30 (27%)