Protein Alignment bin and FOXF2

DIOPT Version :9

• Sequence 1: NP_523950.2
• Gene: bin / 38766
• FlyBaseID: FBgn0045759
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: NP_001443.1
• Gene: FOXF2 / 2295
• HGNCID: 3810
• Length: 444
• Species: Homo sapiens
• Alignment Length: 473
• Identity: 167/473 - (35%)
• Similarity: 220/473 - (46%)
• Gaps: 105/473 - (22%)

  Fly   211 PQQLPAQQLQHSPGGGYMSRISTSPSQVISNAHGMPVLNYSSSSSSPAKSLNGSES----SPPSQ 271
            |...|.::......|...:.:.:.|....:.|...|....||||||.|...:.|.|    |.||.
Human     7 PPPAPLRRACSPVPGALQAALMSPPPAAAAAAAAAPETTSSSSSSSSASCASSSSSSNSASAPSA 71

  Fly   272 NHLENKVSGSAVVGTGGSSQQDAPSTPDTTKKSGTRRPEKPALSYINMIGHAIKESPTGKLTLSE 336
             ..::...|.|..|:||:.:          ..||.||||||..|||.:|..||:.||:.:|||||
Human    72 -ACKSAGGGGAGAGSGGAKK----------ASSGLRRPEKPPYSYIALIVMAIQSSPSKRLTLSE 125

  Fly   337 IYAYLQKSYEFFRGPYVGWKNSVRHNLSLNECFKKLPKGMGVGKPGKGNYWTIDENSAHLFEDEG 401
            ||.:||..:.||||.|.||||||||||||||||.|||||:  |:||||:|||||..|..:|| ||
Human   126 IYQFLQARFPFFRGAYQGWKNSVRHNLSLNECFIKLPKGL--GRPGKGHYWTIDPASEFMFE-EG 187

  Fly   402 SLRRRPRGYRSKIK-VKP-YAGHANGYYASGYGDAGMDNGNYYASPAFASYDYSAAGATG---VS 461
            |.||||||:|.|.: :|| |....:|.   |:|.:.:..|..:.:|..|.....:.|..|   :.
Human   188 SFRRRPRGFRRKCQALKPMYHRVVSGL---GFGASLLPQGFDFQAPPSAPLGCHSQGGYGGLDMM 249

  Fly   462 PAG-GQGFADPWNAHAAH------------SGSS-------SVGVGMGVGPLPQYTNISCLAAGG 506
            ||| ..|...|.:||..|            .||:       ..|.| |||           ||||
Human   250 PAGYDAGAGAPSHAHPHHHHHHHVPHMSPNPGSTYMASCPVPAGPG-GVG-----------AAGG 302

  Fly   507 NVNG-----SATTPPLAHSALGMA-----PSASSS---SSPLGAAATLQSDYAPTASLVAAGYSY 558
            ...|     |:::|..:..|:..|     |..|.:   ||| ||:..|:...|.|.|     .:.
Human   303 GGGGDYGPDSSSSPVPSSPAMASAIECHSPYTSPAAHWSSP-GASPYLKQPPALTPS-----SNP 361

  Fly   559 ATSAGSLDNGLRSISLQQLPGLSSIQHAQAQAQAQAHHHHHQHHAS------------------H 605
            |.||| |.:.:.|.||:|     |..|..|:.........:|||::                  |
Human   362 AASAG-LHSSMSSYSLEQ-----SYLHQNAREDLSVGLPRYQHHSTPVCDRKDFVLNFNGISSFH 420

  Fly   606 PSHSHQGHGSMHQNHGTS 623
            ||.|    ||.:.:|..|
Human   421 PSAS----GSYYHHHHQS 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bin	NP_523950.2	Forkhead	311..399	CDD:278670	57/87 (66%)
FOXF2	NP_001443.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	32..98		22/76 (29%)
		FH	100..188	CDD:214627	59/90 (66%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	256..323		19/78 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	338..367		13/35 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	180	1.000	Inparanoid score	I4009
Isobase	1	0.950	-	0	Normalized mean entropy	S2973
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm42168
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR46262
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1971
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	5.100