| Sequence 1: | NP_523950.2 | Gene: | bin / 38766 | FlyBaseID: | FBgn0045759 | Length: | 676 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_032618.2 | Gene: | Foxc1 / 17300 | MGIID: | 1347466 | Length: | 553 | Species: | Mus musculus |
| Alignment Length: | 514 | Identity: | 138/514 - (26%) |
|---|---|---|---|
| Similarity: | 193/514 - (37%) | Gaps: | 161/514 - (31%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 224 GGGYMSRISTSPSQVISN-AHGMPVLNYSSSSSSPAKSLNGSESSPPSQNHLENKVSGSAVVGTG 287
Fly 288 GSSQQDAPSTPDTTKKSGTRRPEKPALSYINMIGHAIKESPTGKLTLSEIYAYLQKSYEFFRGPY 352
Fly 353 VGWKNSVRHNLSLNECFKKLPKGMGVGKPGKGNYWTIDENSAHLFEDEGSLRRRPRGYRSKIKVK 417
Fly 418 ---------------PYAGH----ANGYYASGYGD-----------------------------A 434
Fly 435 GMDNGNYYASPAFASYDYSAAG-ATGVSPAGGQGFADPWNAHAA-------------HSGSSSVG 485
Fly 486 VGMGVGPLPQYTNISCLAAGGNVNGSATTPPLAHSALGMAPSASSSS-----SPLGAAATLQSDY 545
Fly 546 AP-TASLVAAGYSYATSAGSLDNGLRSISLQQLPGLSSIQHAQAQAQAQAHHHHHQHHASHPSHS 609
Fly 610 HQGHGSMHQNHGTSSTTPPPSQSGGSHGIDHSPIDRKPAY-LPPISPPPMMVALNGGGG 667 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| bin | NP_523950.2 | Forkhead | 311..399 | CDD:278670 | 43/87 (49%) |
| Foxc1 | NP_032618.2 | Required for transcriptional activation. /evidence=ECO:0000250|UniProtKB:Q12948 | 1..51 | 7/18 (39%) | |
| FH | 78..166 | CDD:214627 | 44/90 (49%) | ||
| Nuclear localization signal 1 (NLS 1). /evidence=ECO:0000250|UniProtKB:Q12948 | 78..93 | 8/14 (57%) | |||
| Nuclear localization signal 2 (NLS 2). /evidence=ECO:0000250|UniProtKB:Q12948 | 168..176 | 3/7 (43%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 173..326 | 33/170 (19%) | |||
| Required for transcriptional inhibition. /evidence=ECO:0000250|UniProtKB:Q12948 | 217..366 | 37/171 (22%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 356..393 | 10/41 (24%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 420..466 | 14/41 (34%) | |||
| Required for transcriptional activation. /evidence=ECO:0000250|UniProtKB:Q12948 | 466..553 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E2759_KOG2294 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||