DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bin and Foxi1

DIOPT Version :9

Sequence 1:	NP_523950.2	Gene:	bin / 38766	FlyBaseID:	FBgn0045759	Length:	676	Species:	Drosophila melanogaster
Sequence 2:	NP_076396.3	Gene:	Foxi1 / 14233	MGIID:	1096329	Length:	372	Species:	Mus musculus

Alignment Length:	355	Identity:	101/355 - (28%)
Similarity:	157/355 - (44%)	Gaps:	71/355 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   211 PQQLPAQQLQHS-PGGGYMSRISTSPSQVISNAHGMPVLNYSSSSSSPAKSLNGSESSP--PSQN 272
            ||.:|:.|...| .|||   ...|:|:         |.|..:..:.:|...|.|:.:||  |...
Mouse    38 PQGMPSPQRPTSFEGGG---EYGTTPN---------PYLWLNGPAMTPPPYLPGTNASPFLPQAY 90

  Fly   273 HLENKVSGSAVVGTGGSSQQDAPSTPDTTKKSGTRRPEKPALSYINMIGHAIKESPTGKLTLSEI 337
            .::.::..|.:......||::            ..:..:|..||..:|..||..:|..:||||:|
Mouse    91 GMQRQLLPSDLGWLPIPSQEE------------LMKLVRPPYSYSALIAMAIHGAPDQRLTLSQI 143

  Fly   338 YAYLQKSYEFFRGPYVGWKNSVRHNLSLNECFKKLPKGMGVGKPGKGNYWTIDENSAHLFEDEGS 402
            |.|:..::.|:.....||:||:|||||||:||||:|:  ....||||||||:|.|...:| |.|:
Mouse   144 YQYVADNFPFYNKSKAGWQNSIRHNLSLNDCFKKVPR--DEDDPGKGNYWTLDPNCEKMF-DNGN 205

  Fly   403 LRRRPRGYRSKIKVKPYAGHANGYYASGYGDAGMDNGNYYASPA---------FASYDYSAAG-- 456
            .||       |.|.|..:..:....||    ...:||...:||.         .||.|.:.:.
Mouse   206 FRR-------KRKRKSDSSSSTSSLAS----EKTENGLLASSPKPTEPQEVLDTASPDTTTSSPE 259

  Fly   457 -ATGVSPAGG---QGFADPWNAHAAHSGSSSVGV---GMGVGPLPQ----------YTNISCLAA 504
             .:..:|:|.   ..|.....|:.:.:...|..|   |:...|:.:          ||.::.|::
Mouse   260 KRSSPAPSGTPCLNNFLSTMTAYVSGTNPISRSVATPGLSSEPIDKMGQNSLNFNSYTPLTNLSS 324

  Fly   505 GGNVNGSATTPPLAHSALGMAPSASSSSSP 534
            .|  ||.....|:|.:|||...|..:..||
Mouse   325 HG--NGGEWANPVATNALGYGGSVFNQFSP 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bin	NP_523950.2	Forkhead	311..399	CDD:278670	42/87 (48%)
Foxi1	NP_076396.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..23
		FH	117..205	CDD:214627	43/90 (48%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	202..271		18/79 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810