Protein Alignment bin and FOXN3

DIOPT Version :10

• Sequence 1: NP_523950.2
• Gene: bin / 38766
• FlyBaseID: FBgn0045759
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: NP_001078940.1
• Gene: FOXN3 / 1112
• HGNCID: 1928
• Length: 490
• Species: Homo sapiens
• Alignment Length: 532
• Identity: 124/532 - (23%)
• Similarity: 181/532 - (34%)
• Gaps: 160/532 - (30%)

  Fly   196 DYQLLTSQEQAGQQQPQQLPAQQLQHSPGGGYMSRISTSPSQVISNAHGMPVLNYSSSSSSPAKS 260
            |:.|...:.:.|..:.::|......|.             |:.:..:.|..||.    |.||.:.
Human    42 DFSLPDIRLEEGAMEDEELTNLNWLHE-------------SKNLLKSFGESVLR----SVSPVQD 89

  Fly   261 LNGSESSPPSQNHLENKVSGSAVVGTGGSSQQDAPSTPDTTKKSGTRRPEKPALSYINMIGHAIK 325
            |:  :.:|||..|              .....||...|:.          ||..|:..:|..||:
Human    90 LD--DDTPPSPAH--------------SDMPYDARQNPNC----------KPPYSFSCLIFMAIE 128

  Fly   326 ESPTGKLTLSEIYAYLQKSYEFFRGPYVGWKNSVRHNLSLNECFKKLPKGMGVGKPGKGNYWTID 390
            :|||.:|.:.:||.::.:.:.:|.....|||||||||||||:||||:.|... ...|||:.|.||
Human   129 DSPTKRLPVKDIYNWILEHFPYFANAPTGWKNSVRHNLSLNKCFKKVDKERS-QSIGKGSLWCID 192

  Fly   391 ENSAHLFEDEGSLRRRPRGYRSK----IKVKPYAGHANGY---------YASGYGD---AGMD-- 437
            ..                 ||..    :|..||..|.:.:         |.|..|.   .|..
Human   193 PE-----------------YRQNLIQALKKTPYHPHPHVFNTPPTCPQAYQSTSGPPIWPGSTFF 240

  Fly   438 --NGNYYASPAFASYDYSAAGA---TGVSPAGGQGFADPWNAHAAHSGSSSVGVGM--GVGPLPQ 495
              ||.....|     |..||.|   ....|....||.    .....:|:..:..|:  ||.|||
Human   241 KRNGALLQDP-----DIDAASAMMLLNTPPEIQAGFP----PGVIQNGARVLSRGLFPGVRPLP- 295

  Fly   496 YTNISCLAAGGN-------------------VNGSATTPPLAHSALGMAPSASSSSSPLGAAATL 541
            .|.|...||..|                   |:|.   |...|:......|.:.|:||...:.:.
Human   296 ITPIGVTAAMRNGITSCRMRTESEPSCGSPVVSGD---PKEDHNYSSAKSSNARSTSPTSDSISS 357

  Fly   542 QSDYAPTASLVAAGYSYAT------SAGSLDNGLRSISLQQLPGLSSIQHAQAQAQAQAHHHHHQ 600
            .|..|..      .|.:||      |.|| :...||             |   ::.:.......:
Human   358 SSSSADD------HYEFATKGSQEGSEGS-EGSFRS-------------H---ESPSDTEEDDRK 399

  Fly   601 HHASHPSHS--HQGHGSMH--QNHGTSSTTPPPSQSGGSHGIDHSPIDRKPAYLPPISPPPMMVA 661
            |....|..|  ..|:.|.|  :.|...:...|.         |..|:.::....||.|....|..
Human   400 HSQKEPKDSLGDSGYASQHKKRQHFAKARKVPS---------DTLPLKKRRTEKPPESDDEEMKE 455

  Fly   662 LNGGGGYYEGLK 673
            ..|...:..|::
Human   456 AAGSLLHLAGIR 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bin	NP_523950.2	FH_FOX	312..391	CDD:469596	35/78 (45%)
FOXN3	NP_001078940.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	86..108		7/37 (19%)
		FH_FOXN3	114..203	CDD:410833	39/106 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	315..458		33/177 (19%)