DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Galphai and gnaz

DIOPT Version :9

Sequence 1:	NP_477502.1	Gene:	Galphai / 38765	FlyBaseID:	FBgn0001104	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	XP_005155690.2	Gene:	gnaz / 564915	ZFINID:	ZDB-GENE-090420-3	Length:	355	Species:	Danio rerio

Alignment Length:	355	Identity:	220/355 - (61%)
Similarity:	271/355 - (76%)	Gaps:	2/355 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGCAVSTARDKEAIERSKNIDRALRAEGERAASEVKLLLLGAGESGKSTIVKQMKIIHDTGYSQE 65
            |||..|| .:|||..||:.|||.||:|.:|...|:||||||...||||||||||||||..|::.|
Zfish     1 MGCRQST-EEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLE 64

  Fly    66 ECEEYRRVVFSNTVQSLMVIIRAMGRLKIEFADPSRTDIARQFFTHASAAD-EGILLPEIVLLMK 129
            .|:||:.::..|.:.||..||||:..|||:|.:|.|...|.|.|.....|: :|.:.||::.:||
Zfish    65 ACKEYKPLILYNAIDSLTRIIRALATLKIDFHNPDRAYDAVQLFALTGPAESKGEITPELLGVMK 129

  Fly   130 KLWADGGVQQSFARSREYQLNDSAGYYLNSLDRIAQPNYIPTQQDVLRTRVKTTGIIETHFSCKQ 194
            :||||.|||:.|.||.||.|.|:..||||.||||:.|.||||.:|:||:|..||||:|..|:.|:
Zfish   130 RLWADPGVQECFCRSNEYHLEDNTAYYLNDLDRISAPEYIPTVEDILRSRDMTTGIVENKFTFKE 194

  Fly   195 LHFKLFDVGGQRSERKKWIHCFEGVTAIIFCVALSGYDLVLAEDEEMNRMIESLKLFDSICNSKW 259
            |.||:.||||||||||||||||||||||||||.||||||.|.||.:.:||.|||:|||||||:.|
Zfish   195 LTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSICNNNW 259

  Fly   260 FVETSIILFLNKKDLFEEKIKRSPLTICFPEYTGTNTFEEAANYIRMKFENLNKRKDQKEIYTHL 324
            |..||:|||||||||..|||||.|||:||.:|.|.||:||||.|::.:||:||:.|:.||||:|.
Zfish   260 FTNTSLILFLNKKDLLAEKIKRIPLTVCFADYKGQNTYEEAAVYVQRQFEDLNRNKETKEIYSHF 324

  Fly   325 TCATDTNNVKFVFDAVTDVIIKNNLKQIGL 354
            ||||||:|::|||||||||||:||||.|||
Zfish   325 TCATDTSNIQFVFDAVTDVIIQNNLKYIGL 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Galphai	NP_477502.1	G_alpha	14..353	CDD:214595	209/339 (62%)
Galphai	NP_477502.1	G-alpha	35..349	CDD:206639	196/314 (62%)
gnaz	XP_005155690.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D406662at33208
OrthoFinder	1	1.000	-	-		FOG0000052
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.930