DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Galphai and gna14a

DIOPT Version :9

Sequence 1:	NP_477502.1	Gene:	Galphai / 38765	FlyBaseID:	FBgn0001104	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	XP_683989.2	Gene:	gna14a / 556160	ZFINID:	ZDB-GENE-081105-76	Length:	354	Species:	Danio rerio

Alignment Length:	355	Identity:	170/355 - (47%)
Similarity:	234/355 - (65%)	Gaps:	6/355 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 GCAVSTARDKEAIERSKNIDRALRAEGERAASEVKLLLLGAGESGKSTIVKQMKIIHDTGYSQEE 66
            ||.:| |.:||....::.||:.||.:.:.:..|:||||||.|||||||.:|||:|||.:||:.::
Zfish     3 GCCMS-AEEKERQRINQEIDKQLRKDKKDSRRELKLLLLGTGESGKSTFIKQMRIIHGSGYTDDD 66

  Fly    67 CEEYRRVVFSNTVQSLMVIIRAMGRLKIEFADPSRTDIARQFFTHASAADEGILLPEI-VLLMKK 130
            .:.:.::|..||:.::..::|||..|||.:|:....  |.....:....|:.:.|.|. |..:..
Zfish    67 KKGFIKLVHQNTLSAMQSMVRAMDMLKIAYANSENQ--AHSALVNDIEVDKIMSLDETQVKALSS 129

  Fly   131 LWADGGVQQSFARSREYQLNDSAGYYLNSLDRIAQPNYIPTQQDVLRTRVKTTGIIETHFSCKQL 195
            ||:|.|:|:.:.|.|||||.|||.|||:.|||||...|:||:||:||.||.||||||..|....:
Zfish   130 LWSDSGIQECYDRRREYQLTDSAKYYLSDLDRIANAAYVPTEQDILRVRVPTTGIIEYPFDLDNV 194

  Fly   196 HFKLFDVGGQRSERKKWIHCFEGVTAIIFCVALSGYDLVLAEDEEMNRMIESLKLFDSICNSKWF 260
            .|::.|||||||||:|||||||.||:|||.||||.||.||||.:..|||.||..||.:|....||
Zfish   195 IFRMVDVGGQRSERRKWIHCFENVTSIIFLVALSEYDQVLAECDNENRMEESKALFKTIITYPWF 259

  Fly   261 VETSIILFLNKKDLFEEKIKRSPLTICFPEYTGTNTFEEAA-NYIRMKFENLNKRKDQKEIYTHL 324
            ..:|:||||||.|:.:|||..|.:...|||:||.....:|| .:|...::..|:.|| |.||:|.
Zfish   260 QSSSVILFLNKTDILKEKIVYSHVATYFPEFTGPKNDPKAAQEFILKMYQEENEDKD-KTIYSHF 323

  Fly   325 TCATDTNNVKFVFDAVTDVIIKNNLKQIGL 354
            ||||||.|::.:|.||.|.|:::|||:..|
Zfish   324 TCATDTENIRLIFAAVKDTILRHNLKEFNL 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Galphai	NP_477502.1	G_alpha	14..353	CDD:214595	163/340 (48%)
Galphai	NP_477502.1	G-alpha	35..349	CDD:206639	155/315 (49%)
gna14a	XP_683989.2	G_alpha	15..352	CDD:214595	163/339 (48%)
gna14a	XP_683989.2	G-alpha	35..348	CDD:206639	155/315 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586306
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	1	1.000	-	-		FOG0000052
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.860