DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Galphai and gna14

DIOPT Version :9

Sequence 1:	NP_477502.1	Gene:	Galphai / 38765	FlyBaseID:	FBgn0001104	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	NP_001008054.1	Gene:	gna14 / 493416	XenbaseID:	XB-GENE-945095	Length:	354	Species:	Xenopus tropicalis

Alignment Length:	355	Identity:	173/355 - (48%)
Similarity:	238/355 - (67%)	Gaps:	6/355 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 GCAVSTARDKEAIERSKNIDRALRAEGERAASEVKLLLLGAGESGKSTIVKQMKIIHDTGYSQEE 66
            ||.: ||.:||:...:..|::.||.:...|..|:||||||.|||||||.:|||:|||.:||:.|:
Frog     3 GCCL-TAEEKESQRINAEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYTDED 66

  Fly    67 CEEYRRVVFSNTVQSLMVIIRAMGRLKIEFADPSRTDIARQFFTHASAADE-GILLPEIVLLMKK 130
            .:.:.::|:.|...|:..:||||..|:|:::  |..::...........|: ..|..:.|..:||
Frog    67 RKGFTKLVYQNIFTSMQAMIRAMDTLRIQYS--SEQNMENALTVREVEVDKVSSLERKHVEAIKK 129

  Fly   131 LWADGGVQQSFARSREYQLNDSAGYYLNSLDRIAQPNYIPTQQDVLRTRVKTTGIIETHFSCKQL 195
            ||.|.|:|:.:.|.|||||:||..|||:.:|||:.|::|||||||||.||.||||||..|..:.:
Frog   130 LWEDEGIQECYDRRREYQLSDSTKYYLSDIDRISNPSFIPTQQDVLRVRVPTTGIIEYPFDLENI 194

  Fly   196 HFKLFDVGGQRSERKKWIHCFEGVTAIIFCVALSGYDLVLAEDEEMNRMIESLKLFDSICNSKWF 260
            .|::.|||||||||:|||||||.||:|||.||||.||.||||.:..|||.||..||.:|....||
Frog   195 IFRMVDVGGQRSERRKWIHCFENVTSIIFLVALSEYDQVLAECDNENRMEESKALFRTIITYPWF 259

  Fly   261 VETSIILFLNKKDLFEEKIKRSPLTICFPEYTGTNTFEEAA-NYIRMKFENLNKRKDQKEIYTHL 324
            ..:|:|||||||||.:|||..|.|...|||:||.....::| ::|...:::.|..| :|.||:|.
Frog   260 QNSSVILFLNKKDLLQEKIMYSHLIDYFPEFTGPKQDSQSARDFILKLYQDQNPDK-EKVIYSHF 323

  Fly   325 TCATDTNNVKFVFDAVTDVIIKNNLKQIGL 354
            ||||||.|::|||.||.|.|::.||::..|
Frog   324 TCATDTENIRFVFAAVKDTILQLNLREFNL 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Galphai	NP_477502.1	G_alpha	14..353	CDD:214595	166/340 (49%)
Galphai	NP_477502.1	G-alpha	35..349	CDD:206639	159/315 (50%)
gna14	NP_001008054.1	G-alpha	35..348	CDD:206639	159/315 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	1	1.000	-	-		FOG0000052
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010