DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Galphai and gna14

DIOPT Version :9

Sequence 1:	NP_477502.1	Gene:	Galphai / 38765	FlyBaseID:	FBgn0001104	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	NP_001003753.1	Gene:	gna14 / 445297	ZFINID:	ZDB-GENE-040808-7	Length:	354	Species:	Danio rerio

Alignment Length:	353	Identity:	159/353 - (45%)
Similarity:	224/353 - (63%)	Gaps:	4/353 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 CAVSTARDKEAIERSKNIDRALRAEGERAASEVKLLLLGAGESGKSTIVKQMKIIHDTGYSQEEC 67
            |.:| ..:||.:...:.|:|.|:.:...:..|:||||||.|||||||.:|||:|||..||::|:.
Zfish     4 CCLS-GEEKEKMRIHQEIERKLKMDRRSSNKELKLLLLGTGESGKSTFIKQMRIIHGKGYTEEDK 67

  Fly    68 EEYRRVVFSNTVQSLMVIIRAMGRLKIEFADPSRTDIARQFFTHASAADEGILLPEIVLLMKKLW 132
            ..:.::|:.|...|:..:::||..|||.||: |:.:..........|.....:..:....:|.:|
Zfish    68 RSFAKLVYQNVFTSIQSMLKAMENLKIPFAE-SKNETFAAMLKEVEAESVQTMEAKYAEAIKSVW 131

  Fly   133 ADGGVQQSFARSREYQLNDSAGYYLNSLDRIAQPNYIPTQQDVLRTRVKTTGIIETHFSCKQLHF 197
            .|.|:|:.:.|.|||||:||..|||:.:||||...|:||.||:||.||.||||||..|..:.:.|
Zfish   132 KDQGLQKCYERRREYQLSDSTKYYLDDMDRIAAGFYMPTLQDILRVRVPTTGIIEYVFDLQSVLF 196

  Fly   198 KLFDVGGQRSERKKWIHCFEGVTAIIFCVALSGYDLVLAEDEEMNRMIESLKLFDSICNSKWFVE 262
            ::.|||||:|||:|||||||.||::||.||||.||..|.|....|||.||..||.:|.:..||.:
Zfish   197 RMVDVGGQKSERRKWIHCFENVTSVIFLVALSEYDQFLFESANENRMEESKALFKTIISYPWFQD 261

  Fly   263 TSIILFLNKKDLFEEKIKRSPLTICFPEYTG-TNTFEEAANYIRMKFENLNKRKDQKEIYTHLTC 326
            :|:||||||.|:.::||.:|.|...:|::|| .|..:.|..:|...:|..|..| ||.||.|.||
Zfish   262 SSVILFLNKTDILKDKILKSDLAKYYPQFTGPKNDADAAMKFILKMYEEQNPDK-QKRIYAHFTC 325

  Fly   327 ATDTNNVKFVFDAVTDVIIKNNLKQIGL 354
            ||||.|::|||:||.|.|::|.|....|
Zfish   326 ATDTENIRFVFEAVKDTILRNTLSAFNL 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Galphai	NP_477502.1	G_alpha	14..353	CDD:214595	154/339 (45%)
Galphai	NP_477502.1	G-alpha	35..349	CDD:206639	149/314 (47%)
gna14	NP_001003753.1	G_alpha	15..348	CDD:214595	153/334 (46%)
gna14	NP_001003753.1	G-alpha	35..348	CDD:206639	149/314 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586304
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	1	1.000	-	-		FOG0000052
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100285
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.660