DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Galphai and gna15.1

DIOPT Version :9

Sequence 1:	NP_477502.1	Gene:	Galphai / 38765	FlyBaseID:	FBgn0001104	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	NP_001003626.2	Gene:	gna15.1 / 445232	ZFINID:	ZDB-GENE-040801-146	Length:	367	Species:	Danio rerio

Alignment Length:	374	Identity:	162/374 - (43%)
Similarity:	226/374 - (60%)	Gaps:	28/374 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGC---------AVSTARDKEAIERSKNIDRALRAEGERAASEVKLLLLGAGESGKSTIVKQMKI 56
            |||         ...:..||.||.....|.|.|..:.:|...|:|:||||.|||||:|.:|||:|
Zfish     1 MGCWRWCYTTCICCLSEEDKNAIVIHNEIKRILAEQKKRERREIKVLLLGTGESGKTTFIKQMRI 65

  Fly    57 IHDTGYSQEECEEYRRVVFSNTVQSLMVIIRAMGRLKIEFADPSRTDIARQFFTHASAADEGILL 121
            ||..|:|:|:...|.:.|:.|...::..:..||..|:|.:|:|......|||        :.:.:
Zfish    66 IHGKGFSEEDRRGYIKNVYQNIFTAMRAMTGAMESLRIPYANPQNEAYGRQF--------KDVEI 122

  Fly   122 PEIVLL-------MKKLWADGGVQQSFARSREYQLNDSAGYYLNSLDRIAQPNYIPTQQDVLRTR 179
            .::..|       :::||||.|::..:.|.|||||.||..||:.:|||||.|:||||.|||||.|
Zfish   123 RQVTQLDRMYVEAIRRLWADPGIKACYCRRREYQLLDSTEYYMTNLDRIAAPDYIPTAQDVLRVR 187

  Fly   180 VKTTGIIETHFSCKQLHFKLFDVGGQRSERKKWIHCFEGVTAIIFCVALSGYDLVLAEDEEMNRM 244
            ..||||.:..||.:::..::.|||||:|||:|||||||.||::||..:||.||.||.|:.:.|||
Zfish   188 FPTTGINDYSFSVEKITLRIVDVGGQKSERRKWIHCFENVTSLIFLASLSEYDQVLEENSKENRM 252

  Fly   245 IESLKLFDSICNSKWFVETSIILFLNKKDLFEEKIKRSPLTICFPEYTG-TNTFEEAANYIRMKF 308
            .|||.||.:..:|.||...||||||||.|:.||||:.|.|...|||:.| ....::|.:||...:
Zfish   253 KESLSLFYTTIHSPWFASASIILFLNKMDILEEKIQSSDLKAYFPEFQGRRRDVQDAKSYISHLY 317

  Fly   309 ENLNK---RKDQKEIYTHLTCATDTNNVKFVFDAVTDVIIKNNLKQIGL 354
            |...|   .|..|:||.|.||||||||::.||..|.|.::..:|::.|:
Zfish   318 EQKAKCTETKTSKQIYPHFTCATDTNNIRKVFGDVKDTVLIRSLREYGV 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Galphai	NP_477502.1	G_alpha	14..353	CDD:214595	155/349 (44%)
Galphai	NP_477502.1	G-alpha	35..349	CDD:206639	148/324 (46%)
gna15.1	NP_001003626.2	G-alpha	44..361	CDD:206639	148/324 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586241
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	1	1.000	-	-		FOG0000052
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.860