DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Galphai and gnaia

DIOPT Version :9

Sequence 1:	NP_477502.1	Gene:	Galphai / 38765	FlyBaseID:	FBgn0001104	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	NP_942100.1	Gene:	gnaia / 323509	ZFINID:	ZDB-GENE-030131-2229	Length:	377	Species:	Danio rerio

Alignment Length:	355	Identity:	263/355 - (74%)
Similarity:	306/355 - (86%)	Gaps:	1/355 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGCAVSTARDKEAIERSKNIDRALRAEGERAASEVKLLLLGAGESGKSTIVKQMKIIHDTGYSQE 65
            |||.:| :.||.|.||||.|||.||.:||:|:.|||||||||||||||||||||||||:.|||:|
Zfish    24 MGCTLS-SDDKSAQERSKMIDRNLRDDGEKASREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEE 87

  Fly    66 ECEEYRRVVFSNTVQSLMVIIRAMGRLKIEFADPSRTDIARQFFTHASAADEGILLPEIVLLMKK 130
            ||::||.||:|||:||::.||||||||:|:||||.|.|.|||.|..|.:.|||.:..|:..::|:
Zfish    88 ECKQYRVVVYSNTIQSIIAIIRAMGRLRIDFADPERADDARQLFVMAGSVDEGFMTSELAGVIKR 152

  Fly   131 LWADGGVQQSFARSREYQLNDSAGYYLNSLDRIAQPNYIPTQQDVLRTRVKTTGIIETHFSCKQL 195
            ||.|.||:..|.|||||||||||.||||.||||:..:|:||||||||||||||||:||||:.|.|
Zfish   153 LWRDEGVRLCFHRSREYQLNDSASYYLNDLDRISNSSYVPTQQDVLRTRVKTTGIVETHFTFKDL 217

  Fly   196 HFKLFDVGGQRSERKKWIHCFEGVTAIIFCVALSGYDLVLAEDEEMNRMIESLKLFDSICNSKWF 260
            |||:|||||||||||||||||||||:|||||:||.||||||||||||||.||:||||||||:|||
Zfish   218 HFKMFDVGGQRSERKKWIHCFEGVTSIIFCVSLSDYDLVLAEDEEMNRMHESMKLFDSICNNKWF 282

  Fly   261 VETSIILFLNKKDLFEEKIKRSPLTICFPEYTGTNTFEEAANYIRMKFENLNKRKDQKEIYTHLT 325
            .:|||||||||||||||||:.|||:||||||.|::.:||||.||:.:||:||||||.||||:|.|
Zfish   283 TDTSIILFLNKKDLFEEKIRMSPLSICFPEYPGSDVYEEAAAYIQCQFEDLNKRKDTKEIYSHFT 347

  Fly   326 CATDTNNVKFVFDAVTDVIIKNNLKQIGLF 355
            |||||.||:||||||||||||||||..|||
Zfish   348 CATDTKNVQFVFDAVTDVIIKNNLKDCGLF 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Galphai	NP_477502.1	G_alpha	14..353	CDD:214595	253/338 (75%)
Galphai	NP_477502.1	G-alpha	35..349	CDD:206639	237/313 (76%)
gnaia	NP_942100.1	G_alpha	37..375	CDD:214595	253/337 (75%)
gnaia	NP_942100.1	G-alpha	57..371	CDD:206639	237/313 (76%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	522	1.000	Domainoid score	I284
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	554	1.000	Inparanoid score	I1088
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D406662at33208
OrthoFinder	1	1.000	-	-		FOG0000052
OrthoInspector	1	1.000	-	-		otm25232
orthoMCL	1	0.900	-	-		OOG6_100285
Panther	1	1.100	-	-	O	PTHR10218
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.840