Protein Alignment Galphai and GNAL

DIOPT Version :9

• Sequence 1: NP_477502.1
• Gene: Galphai / 38765
• FlyBaseID: FBgn0001104
• Length: 355
• Species: Drosophila melanogaster
• Sequence 2: NP_892023.1
• Gene: GNAL / 2774
• HGNCID: 4388
• Length: 458
• Species: Homo sapiens
• Alignment Length: 385
• Identity: 153/385 - (39%)
• Similarity: 216/385 - (56%)
• Gaps: 54/385 - (14%)

  Fly     8 ARDKEAIER----SKNIDRALRAEGERAASEVKLLLLGAGESGKSTIVKQMKIIHDTGYSQEECE 68
            |:::||::.    |:.|||.||.:........:||||||||||||||||||:|:|..|::.||.:
Human    89 AKEREAVKEARKVSRGIDRMLRDQKRDLQQTHRLLLLGAGESGKSTIVKQMRILHVNGFNPEEKK 153

  Fly    69 EYRRVVFSNTVQSLMVIIRAMGRL--KIEFADPS---RTD------------IARQFFTHASAAD 116
            :....:..|...:::.|:.||..:  .:..|:|.   |:|            .:::||.|
Human   154 QKILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSIAPITDFEYSQEFFDH----- 213

  Fly   117 EGILLPEIVLLMKKLWADGGVQQSFARSREYQLNDSAGYYLNSLDRIAQPNYIPTQQDVLRTRVK 181
                       :||||.|.||:..|.||.||||.|.|.|:|..:|.::..:|.||.||:||.||.
Human   214 -----------VKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVL 267

  Fly   182 TTGIIETHFSCKQLHFKLFDVGGQRSERKKWIHCFEGVTAIIFCVALSGYDLVLAEDEEMNRMIE 246
            |:||.||.|...:::|.:|||||||.||:|||.||..|||||:..|.|.|::|:.||...||:.|
Human   268 TSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRLRE 332

  Fly   247 SLKLFDSICNSKWFVETSIILFLNKKDLFEEKI--KRSPLTICFPEYTGTNTFEEAAN------- 302
            ||.||:||.|::|....||||||||:|:..||:  .:|.:...||||......|:|..
Human   333 SLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGEDPK 397

  Fly   303 ------YIRMKFENLNKRK-DQKE-IYTHLTCATDTNNVKFVFDAVTDVIIKNNLKQIGL 354
                  :||..|..::... |.|. .|.|.|||.||.|::.||:...|:|.:.:|||..|
Human   398 VTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLKQYEL 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galphai	NP_477502.1	G_alpha	14..353	CDD:214595	149/376 (40%)
		G-alpha	35..349	CDD:206639	140/347 (40%)
GNAL	NP_892023.1	G_alpha	99..455	CDD:214595	148/371 (40%)
		G-alpha	120..452	CDD:206639	140/347 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820