DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Galphai and CG30054

DIOPT Version :9

Sequence 1:	NP_477502.1	Gene:	Galphai / 38765	FlyBaseID:	FBgn0001104	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	NP_001036538.3	Gene:	CG30054 / 246420	FlyBaseID:	FBgn0050054	Length:	353	Species:	Drosophila melanogaster

Alignment Length:	364	Identity:	161/364 - (44%)
Similarity:	215/364 - (59%)	Gaps:	20/364 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGCAVSTARDKEAIER---SKNIDRALRAEGERAASEVKLLLLGAGESGKSTIVKQMKIIHDTGY 62
            |.|..||    ||:|:   ::.||:.||.|.:|:..|:|||||||.||||||.:|||:|||.:||
  Fly     1 MHCCSST----EAMEKRRINEEIDKQLRLEKKRSKRELKLLLLGACESGKSTFIKQMRIIHGSGY 61

  Fly    63 SQEECEEYRRVVFSNTVQSLMVIIRAMGRLKIEFADPSRTDIAR-----QFFTHASAADEGILLP 122
            |.|:...|.::||.|...::..:|:||..|||.:.....:::|.     .:.|..:..|
  Fly    62 SDEDKRGYIKLVFQNIFMAMQSMIKAMDMLKISYGQGEHSELADLVMSIDYETVTTFED------ 120

  Fly   123 EIVLLMKKLWADGGVQQSFARSREYQLNDSAGYYLNSLDRIAQPNYIPTQQDVLRTRVKTTGIIE 187
            ..:..:|.||.|.|:|:.:.|.|||||.||..|:|..:.||.|.:|:||.||:||.|..|..|..
  Fly   121 PYLNAIKTLWHDAGIQECYDRRREYQLTDSTEYFLGDIGRIEQADYLPTNQDILRAREPTFNITV 185

  Fly   188 THFSCKQLHFKLFDVGGQRSERKKWIHCFEGVTAIIFCVALSGYDLVLAEDEEMNRMIESLKLFD 252
            ..|........:.||.|||:||:||||.|..||:|||..|||.||..:.|.|..||:.||..||.
  Fly   186 YPFELDGYVLSMVDVAGQRTERRKWIHFFSNVTSIIFLAALSEYDQFMMESENDNRLEESKALFH 250

  Fly   253 SICNSKWFVETSIILFLNKKDLFEEKIKRSPLTICFPEYTGTNTFEEAA-NYIRMKFENLNKRKD 316
            :|...:||...||||||||.|:.||||..|.|...||||.|......|| .|:...|:::: ...
  Fly   251 TIITFEWFKNASIILFLNKMDVLEEKIMYSHLVDYFPEYDGPKQDAYAAREYVLRMFQSIS-LDT 314

  Fly   317 QKEIYTHLTCATDTNNVKFVFDAVTDVIIKNNLKQIGLF 355
            .|:||:|.||||||.|:||||.||.|.|::.|||:..||
  Fly   315 YKKIYSHFTCATDTENIKFVFAAVKDTILQCNLKESNLF 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Galphai	NP_477502.1	G_alpha	14..353	CDD:214595	153/347 (44%)
Galphai	NP_477502.1	G-alpha	35..349	CDD:206639	142/319 (45%)
CG30054	NP_001036538.3	G_alpha	13..351	CDD:214595	152/344 (44%)
CG30054	NP_001036538.3	G-alpha	34..347	CDD:206639	142/319 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455800
Domainoid	1	1.000	229	1.000	Domainoid score	I660
eggNOG	1	0.900	-	-		E1_KOG0082
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	233	1.000	Inparanoid score	I1124
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	1	1.000	-	-		FOG0000052
OrthoInspector	1	1.000	-	-		otm3584
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10218
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
	9	8.990