DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Galphai and odr-3

DIOPT Version :9

Sequence 1:	NP_477502.1	Gene:	Galphai / 38765	FlyBaseID:	FBgn0001104	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	NP_506290.1	Gene:	odr-3 / 179806	WormBaseID:	WBGene00003850	Length:	356	Species:	Caenorhabditis elegans

Alignment Length:	356	Identity:	174/356 - (48%)
Similarity:	240/356 - (67%)	Gaps:	3/356 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGCAVSTARDKEAIERSKNIDRALRAEGERAASEVKLLLLGAGESGKSTIVKQMKIIHDTGYSQE 65
            ||...|. .:.|...|:|.|::.|.|:....:|.||||||||||.||||::|||:|:|..|:::|
Worm     1 MGSCQSN-ENSEGNARNKEIEKQLNADKRAGSSIVKLLLLGAGECGKSTVLKQMQILHSNGFTEE 64

  Fly    66 ECEEYRRVVFSNTVQSLMVIIRAM-GRLKIEFADPSRTDIARQFFTHASAADEG-ILLPEIVLLM 128
            |..|.|.:|::|||.::..|:||| |.|.:...:..:..............:|| .|..|:...:
Worm    65 EVNEKRAIVYNNTVSAMCTILRAMDGVLHLPLENGQKEAEKAIVMKVQENGEEGEALTEEVSKAI 129

  Fly   129 KKLWADGGVQQSFARSREYQLNDSAGYYLNSLDRIAQPNYIPTQQDVLRTRVKTTGIIETHFSCK 193
            :.||||.||:::|....||||.|||.|:|::..||::|.|.|..||:|.:||.|||::|..|..|
Worm   130 QSLWADPGVKKAFEMRSEYQLPDSAKYFLDNCQRISEPGYRPNDQDILYSRVATTGVVEVKFKIK 194

  Fly   194 QLHFKLFDVGGQRSERKKWIHCFEGVTAIIFCVALSGYDLVLAEDEEMNRMIESLKLFDSICNSK 258
            :|.|::||||||||||:||||||:.|.:|||..|:|.||.||.|||..||||||::||:|||||.
Worm   195 ELDFRVFDVGGQRSERRKWIHCFDNVESIIFITAISEYDQVLFEDETTNRMIESMQLFNSICNST 259

  Fly   259 WFVETSIILFLNKKDLFEEKIKRSPLTICFPEYTGTNTFEEAANYIRMKFENLNKRKDQKEIYTH 323
            ||:.|::|||:||||||.|||:|..:|..||:|.|...:|||.::|:.||..||...|:|.||.|
Worm   260 WFLSTAMILFMNKKDLFMEKIQRVNITTAFPDYEGGQNYEEAVSFIKQKFAELNLNPDKKTIYMH 324

  Fly   324 LTCATDTNNVKFVFDAVTDVIIKNNLKQIGL 354
            .|||||||.|:.|..:|.|.||:.||::.|:
Worm   325 ETCATDTNQVQLVISSVIDTIIQKNLQKAGM 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Galphai	NP_477502.1	G_alpha	14..353	CDD:214595	169/340 (50%)
Galphai	NP_477502.1	G-alpha	35..349	CDD:206639	161/315 (51%)
odr-3	NP_506290.1	G_alpha	14..354	CDD:214595	169/339 (50%)
odr-3	NP_506290.1	G-alpha	34..350	CDD:206639	161/315 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D406662at33208
OrthoFinder	1	1.000	-	-		FOG0000052
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100285
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R506
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.760