Protein Alignment Galphai and gpa-2

DIOPT Version :10

• Sequence 1: NP_477502.1
• Gene: Galphai / 38765
• FlyBaseID: FBgn0001104
• Length: 355
• Species: Drosophila melanogaster
• Sequence 2: NP_505157.1
• Gene: gpa-2 / 179219
• WormBaseID: WBGene00001664
• Length: 356
• Species: Caenorhabditis elegans
• Alignment Length: 369
• Identity: 163/369 - (44%)
• Similarity: 223/369 - (60%)
• Gaps: 37/369 - (10%)

  Fly     1 MGCAVSTARDKEAIERSKNIDRALRAEGERAASEVKLLLLGAGESGKSTIVKQMKIIHDTGYSQE 65
            :|...|.|.|||.        :.|:...||.   ||||||||||.||||::|||:::....|:.|
 Worm    11 VGTLKSRAIDKEI--------KQLQTSEERT---VKLLLLGAGECGKSTVLKQMRLLTSKQYTDE 64

  Fly    66 ECEEYRRVVFSNTVQSLMVIIRAMGRLKIEFADPSR-----------TDIARQFFTHASAADEGI 119
            |.....::|::|.|..:..:::||....:.|:||.|           .|:..:.| ...|||.
 Worm    65 ELLTQAKLVYTNIVIEMDHLVKAMPAAGLNFSDPMREHDVHMLTLYIKDMQHKNF-QQDAADH-- 126

  Fly   120 LLPEIVLLMKKLWADGGVQQSFARSREY---QLNDSAGYYLNSLDRIAQPNYIPTQQDVLRTRVK 181
                    ::|||.|..|::.:|..:|.   .:.|:..|:..:|.||::.:|.|...|.|..|.|
 Worm   127 --------VEKLWKDPVVKRLYAERKELNIRDIGDNTEYFFENLPRISKEDYHPNATDTLLLRTK 183

  Fly   182 TTGIIETHFSCKQLHFKLFDVGGQRSERKKWIHCFEGVTAIIFCVALSGYDLVLAEDEEMNRMIE 246
            ||||:|..|..|::.|::||||||||||||||||||.|.||||..|||.|:.||.|||..|||||
 Worm   184 TTGIVEVGFEIKKVKFRVFDVGGQRSERKKWIHCFEDVNAIIFIAALSEYNEVLFEDETTNRMIE 248

  Fly   247 SLKLFDSICNSKWFVETSIILFLNKKDLFEEKIKRSPLTICFPEYTGTNTFEEAANYIRMKFENL 311
            |::||:|||||:||..|:||||||||||||||||:..:...||||.|...:.|...:|:.|||.|
 Worm   249 SMRLFESICNSRWFHNTNIILFLNKKDLFEEKIKKENIHKAFPEYRGEQNYAETVAFIKTKFEAL 313

  Fly   312 NKRKDQKEIYTHLTCATDTNNVKFVFDAVTDVIIKNNLKQIGLF 355
            : ...:|..|.|.|||||||.|:.:.|:|..:||::||.:.||:
 Worm   314 S-NNPKKTFYVHETCATDTNQVQKILDSVISMIIQSNLHKSGLY 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galphai	NP_477502.1	G-alpha	35..349	CDD:206639	150/327 (46%)
gpa-2	NP_505157.1	G_alpha	13..354	CDD:214595	160/363 (44%)