DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Galphai and gpa-15

DIOPT Version :9

Sequence 1:	NP_477502.1	Gene:	Galphai / 38765	FlyBaseID:	FBgn0001104	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	NP_492312.1	Gene:	gpa-15 / 172645	WormBaseID:	WBGene00001677	Length:	356	Species:	Caenorhabditis elegans

Alignment Length:	355	Identity:	150/355 - (42%)
Similarity:	228/355 - (64%)	Gaps:	1/355 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGCAVSTARDKEAIERSKNIDRALRAEGERAASEVKLLLLGAGESGKSTIVKQMKIIHDTGYSQE 65
            ||...||...||....:..||:.:|.:.:......||||||.||.|||||:||:.|:|.:|:|:.
Worm     1 MGSTCSTPESKEQKRINSVIDKQIRKDEDDEIGNQKLLLLGTGECGKSTILKQINILHSSGFSKA 65

  Fly    66 ECEEYRRVVFSNTVQSLMVIIRAMGRLKIEFADPSRTDIARQFFTHASAADEGI-LLPEIVLLMK 129
            :.:.....|:||.:|.:..:::|......|.:.|.....|:...:.|.::.:.: .:|.....:|
Worm    66 DLKNVAGTVYSNIIQGVATLLKAKDHFYYELSTPELDADAQHILSLADSSKDAMPFIPLTFNAIK 130

  Fly   130 KLWADGGVQQSFARSREYQLNDSAGYYLNSLDRIAQPNYIPTQQDVLRTRVKTTGIIETHFSCKQ 194
            :||.|..||::|.|..|:|:.|:..|::|.||||...:||||..|:||.|:.|.|:::.....|.
Worm   131 RLWHDPVVQKTFERRAEFQMMDTLVYFMNELDRINNADYIPTVDDMLRIRIPTMGVVQQTIEIKG 195

  Fly   195 LHFKLFDVGGQRSERKKWIHCFEGVTAIIFCVALSGYDLVLAEDEEMNRMIESLKLFDSICNSKW 259
            ..|:::|||||||||:||||.|:.|.|.||..|::.::..|.||.:.|||.||:|||::||||:|
Worm   196 TKFRIYDVGGQRSERRKWIHLFDNVNATIFISAINEFNQKLNEDGQTNRMKESIKLFETICNSRW 260

  Fly   260 FVETSIILFLNKKDLFEEKIKRSPLTICFPEYTGTNTFEEAANYIRMKFENLNKRKDQKEIYTHL 324
            ||:.::||||||:||||:|:|.:.:.:.|..|.|:|.:.|...||:|:||.|||..|.|:||||:
Worm   261 FVQAAMILFLNKRDLFEQKLKTTSINVLFSTYQGSNDYAECVAYIQMRFERLNKYSDIKKIYTHV 325

  Fly   325 TCATDTNNVKFVFDAVTDVIIKNNLKQIGL 354
            |||||||.::.|.|:|.|::|..||:..|:
Worm   326 TCATDTNQIQLVIDSVVDMVIGRNLRGTGM 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Galphai	NP_477502.1	G_alpha	14..353	CDD:214595	143/339 (42%)
Galphai	NP_477502.1	G-alpha	35..349	CDD:206639	138/314 (44%)
gpa-15	NP_492312.1	G_alpha	14..354	CDD:214595	143/339 (42%)
gpa-15	NP_492312.1	G-alpha	35..350	CDD:206639	138/314 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S498
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D406662at33208
OrthoFinder	1	1.000	-	-		FOG0000052
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.780