DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Galphai and egl-30

DIOPT Version :9

Sequence 1:	NP_477502.1	Gene:	Galphai / 38765	FlyBaseID:	FBgn0001104	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	NP_740789.1	Gene:	egl-30 / 171751	WormBaseID:	WBGene00001196	Length:	355	Species:	Caenorhabditis elegans

Alignment Length:	362	Identity:	177/362 - (48%)
Similarity:	237/362 - (65%)	Gaps:	16/362 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGCAVS-TARDKEAIERSKNIDRALRAEGERAASEVKLLLLGAGESGKSTIVKQMKIIHDTGYSQ 64
            |.|.:| .||:::.|  ::.|::.|:.:...|..|:||||||.|||||||.:|||:|||..|||:
Worm     1 MACCLSEEAREQKRI--NQEIEKQLQRDKRNARRELKLLLLGTGESGKSTFIKQMRIIHGQGYSE 63

  Fly    65 EECEEYRRVVFSNTVQSLMVIIRAMGRLKIEFADPS-----RTDIARQF-FTHASAADEGILLPE 123
            |:...:.|:|:.|...::..:||||..|.|:|.:.|     :..:.|:. |...::.:|     .
Worm    64 EDKRAHIRLVYQNVFMAIQSMIRAMDTLDIKFGNESEELQEKAAVVREVDFESVTSFEE-----P 123

  Fly   124 IVLLMKKLWADGGVQQSFARSREYQLNDSAGYYLNSLDRIAQPNYIPTQQDVLRTRVKTTGIIET 188
            .|..:|:||.|.|:|:.:.|.|||||.|||.|||:.|.|:|.|:|:||:||:||.||.||||||.
Worm   124 YVSYIKELWEDSGIQECYDRRREYQLTDSAKYYLSDLRRLAVPDYLPTEQDILRVRVPTTGIIEY 188

  Fly   189 HFSCKQLHFKLFDVGGQRSERKKWIHCFEGVTAIIFCVALSGYDLVLAEDEEMNRMIESLKLFDS 253
            .|..:|:.|::.|||||||||:|||||||.||:|:|.||||.||.||.|.:..|||.||..||.:
Worm   189 PFDLEQIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVECDNENRMEESKALFRT 253

  Fly   254 ICNSKWFVETSIILFLNKKDLFEEKIKRSPLTICFPEYTGTNTFEEAA-NYIRMKFENLNKRKDQ 317
            |....||..:|:|||||||||.||||..|.|...||||.|......|| .:|...|.:||...|
Worm   254 IITYPWFTNSSVILFLNKKDLLEEKILYSHLADYFPEYDGPPRDPIAAREFILKMFVDLNPDAD- 317

  Fly   318 KEIYTHLTCATDTNNVKFVFDAVTDVIIKNNLKQIGL 354
            |.||:|.||||||.|::|||.||.|.|:::|||:..|
Worm   318 KIIYSHFTCATDTENIRFVFAAVKDTILQHNLKEYNL 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Galphai	NP_477502.1	G_alpha	14..353	CDD:214595	171/345 (50%)
Galphai	NP_477502.1	G-alpha	35..349	CDD:206639	163/320 (51%)
egl-30	NP_740789.1	G_alpha	13..353	CDD:214595	171/347 (49%)
egl-30	NP_740789.1	G-alpha	34..349	CDD:206639	163/320 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	1	1.000	-	-		FOG0000052
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.930