DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Galphai and AgaP_AGAP005079

DIOPT Version :9

Sequence 1:	NP_477502.1	Gene:	Galphai / 38765	FlyBaseID:	FBgn0001104	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	XP_001688484.1	Gene:	AgaP_AGAP005079 / 1274760	VectorBaseID:	AGAP005079	Length:	353	Species:	Anopheles gambiae

Alignment Length:	361	Identity:	175/361 - (48%)
Similarity:	231/361 - (63%)	Gaps:	16/361 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGCAVS-TARDKEAIERSKNIDRALRAEGERAASEVKLLLLGAGESGKSTIVKQMKIIHDTGYSQ 64
            |.|.:| .|::::.|  ::.|:|.||.:...|..|:||||||.|||||||.:|||:|||.:|||.
Mosquito     1 MECCLSEEAKEQKRI--NQEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSD 63

  Fly    65 EECEEYRRVVFSNTVQSLMVIIRAMGRLKIEFADPSRTDIARQFFTHA----SAADEGILL--PE 123
            |:...:.::|:.|...::..:||||..|||.::||:..:       ||    |...|.:..  |.
Mosquito    64 EDKRGFIKLVYQNIFMAMQSMIRAMDLLKILYSDPANIE-------HAELIRSVDFETVTTFEPP 121

  Fly   124 IVLLMKKLWADGGVQQSFARSREYQLNDSAGYYLNSLDRIAQPNYIPTQQDVLRTRVKTTGIIET 188
            .|..:|.||||.|:|:.:.|.|||||.|||.|||..:||:|.|||:||:||:||.||.||||||.
Mosquito   122 YVQAIKDLWADAGIQECYDRRREYQLTDSAKYYLMEIDRVAAPNYLPTEQDILRVRVPTTGIIEY 186

  Fly   189 HFSCKQLHFKLFDVGGQRSERKKWIHCFEGVTAIIFCVALSGYDLVLAEDEEMNRMIESLKLFDS 253
            .|..:::.|::.|||||||||:|||||||.||:|||.||||.||.:|.|.|..|||.||..||.:
Mosquito   187 PFDLEEIRFRMVDVGGQRSERRKWIHCFENVTSIIFLVALSEYDQILFESENENRMEESKALFKT 251

  Fly   254 ICNSKWFVETSIILFLNKKDLFEEKIKRSPLTICFPEYTGTNTFEEAANYIRMKFENLNKRKDQK 318
            |....||..:|:|||||||||.||||..|.|...||||.|....:..|....:|..........:
Mosquito   252 IITYPWFQHSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPKHDDVKAREFILKVYLRENPDPDR 316

  Fly   319 EIYTHLTCATDTNNVKFVFDAVTDVIIKNNLKQIGL 354
            ..|:|.||||||.|::|||.||.|.|:::|||:..|
Mosquito   317 MCYSHFTCATDTENIRFVFAAVKDTILQSNLKEYNL 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Galphai	NP_477502.1	G_alpha	14..353	CDD:214595	170/344 (49%)
Galphai	NP_477502.1	G-alpha	35..349	CDD:206639	160/319 (50%)
AgaP_AGAP005079	XP_001688484.1	G_alpha	13..351	CDD:214595	170/346 (49%)
AgaP_AGAP005079	XP_001688484.1	G-alpha	34..347	CDD:206639	160/319 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	1	1.000	-	-		FOG0000052
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X53
TreeFam	0	0.000	Not matched by this tool.
	5	4.930