DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Galphai and vwa1

DIOPT Version :9

Sequence 1:	NP_477502.1	Gene:	Galphai / 38765	FlyBaseID:	FBgn0001104	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	XP_002938896.1	Gene:	vwa1 / 100485693	XenbaseID:	XB-GENE-956807	Length:	496	Species:	Xenopus tropicalis

Alignment Length:	196	Identity:	40/196 - (20%)
Similarity:	76/196 - (38%)	Gaps:	33/196 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 SKNIDRALRAEGER--------AASEVKLLLLGAGESGKSTIVKQMKIIHDTGYSQEECEEYRRV 73
            |:.|.||::...:|        |.|.:|..|.......::.:.|.|..:.| |.|.::..:..::
Frog    96 SQEIQRAIQNIKQRMGDTNTGKALSYIKENLFDERSGSRAEVPKVMVWVTD-GLSTDDISQPMQL 159

  Fly    74 VFSNTVQSLMVIIRAMGR---LKIEFADPSRTDIARQFFTHASAADEGILLPEI------VLLMK 129
            :..   ..:.|.|.:.||   |::..|..:.:|....|   ....|..|:..|:      ::..:
Frog   160 LKD---MGVTVFIVSTGRGNYLELSAAASTPSDTHLHF---VDVDDLHIITKELRDSIIELIRAR 218

  Fly   130 KLWADGGVQQSFARSREYQLNDSAGYYLNSLDRIAQPNYIPTQQDVLRTRVKTTGIIETHFSCKQ 194
            :|.|......||..:....|:...||||...:.::.|.         |...:|....:|.|:.:.
Frog   219 RLHAQDITTTSFRLTWPRLLSKETGYYLLEYELVSDPE---------RKFSRTLSGDQTSFTLQN 274

  Fly   195 L 195
            |
Frog   275 L 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Galphai	NP_477502.1	G_alpha	14..353	CDD:214595	40/196 (20%)
Galphai	NP_477502.1	G-alpha	35..349	CDD:206639	33/170 (19%)
vwa1	XP_002938896.1	vWA_collagen	36..196	CDD:238749	22/106 (21%)
		fn3	218..285	CDD:365830	15/67 (22%)
		FN3	310..394	CDD:238020
		fn3	398..475	CDD:365830
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000052
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.900