DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Galphai and vps72

DIOPT Version :9

Sequence 1:	NP_477502.1	Gene:	Galphai / 38765	FlyBaseID:	FBgn0001104	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	XP_002937316.2	Gene:	vps72 / 100135721	XenbaseID:	XB-GENE-989807	Length:	362	Species:	Xenopus tropicalis

Alignment Length:	162	Identity:	33/162 - (20%)
Similarity:	64/162 - (39%)	Gaps:	40/162 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 YSQEECEEYRRVV---FSNTVQSLMVIIRAMGRLKIEFAD--PSRTDIARQFFTHASAADEGILL 121
            :.::|.::.||||   :...:|.|        :.|.:.||  ||....:|....|....
Frog    73 HEEDEPKKKRRVVTKAYKEPIQLL--------KPKPKKADAPPSSAAKSRPEKPHPQET------ 123

  Fly   122 PEIVLLMKKLWADGGVQ---QSFARSREYQLNDSAGYYLNSLDRIAQPNYIPTQQDVLRTRVKTT 183
            ||..:..:|.......:   |:|.|.:|.|:...         :...|:     ||...|:|:
Frog   124 PEDAVDSRKQMRQSTTEHTRQTFLRVKERQIQSK---------KKKGPH-----QDRPLTQVE-- 172

  Fly   184 GIIETHFSCKQLHFK-LFDVGGQRSERKKWIH 214
             ::|.....::::.: |.:.....::|||.:|
Frog   173 -LLEEAKITEEINIRSLENYERLEADRKKQVH 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Galphai	NP_477502.1	G_alpha	14..353	CDD:214595	33/162 (20%)
Galphai	NP_477502.1	G-alpha	35..349	CDD:206639	33/162 (20%)
vps72	XP_002937316.2	YL1	7..217	CDD:368602	33/162 (20%)
vps72	XP_002937316.2	YL1_C	285..313	CDD:369784
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165170458
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930