DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Galphai and gnat1

DIOPT Version :9

Sequence 1:	NP_477502.1	Gene:	Galphai / 38765	FlyBaseID:	FBgn0001104	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	NP_001096278.1	Gene:	gnat1 / 100124843	XenbaseID:	XB-GENE-1003264	Length:	350	Species:	Xenopus tropicalis

Alignment Length:	355	Identity:	216/355 - (60%)
Similarity:	273/355 - (76%)	Gaps:	5/355 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGCAVSTARDKEAIERSKNIDRALRAEGERAASEVKLLLLGAGESGKSTIVKQMKIIHDTGYSQE 65
            ||...| |.:|    .|:.:::.|:.:.|:.|..||||||||||||||||||||||||..|||.|
Frog     1 MGAGAS-AEEK----HSRELEKKLKEDAEKDARTVKLLLLGAGESGKSTIVKQMKIIHQDGYSLE 60

  Fly    66 ECEEYRRVVFSNTVQSLMVIIRAMGRLKIEFADPSRTDIARQFFTHASAADEGILLPEIVLLMKK 130
            ||.|:..:::.||:||::.|:|||..|.|::.||:|.|.:|:....|...|||.:..|:..::.:
Frog    61 ECLEFISIIYGNTLQSMLAIVRAMNTLNIQYGDPARQDDSRKLLHLADTIDEGSMPKEMSDIIGR 125

  Fly   131 LWADGGVQQSFARSREYQLNDSAGYYLNSLDRIAQPNYIPTQQDVLRTRVKTTGIIETHFSCKQL 195
            ||.|.|:|..|.|:.|||||||||||||.|:|:..|.|:||:|||||:||||||||||.|..|.|
Frog   126 LWKDTGIQACFDRASEYQLNDSAGYYLNDLERLVTPGYVPTEQDVLRSRVKTTGIIETQFGFKDL 190

  Fly   196 HFKLFDVGGQRSERKKWIHCFEGVTAIIFCVALSGYDLVLAEDEEMNRMIESLKLFDSICNSKWF 260
            :|::|||||||||||||||||||||.|||..|||.||:||.||:|:|||.|||.||:||||.::|
Frog   191 NFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDDEVNRMHESLHLFNSICNHRYF 255

  Fly   261 VETSIILFLNKKDLFEEKIKRSPLTICFPEYTGTNTFEEAANYIRMKFENLNKRKDQKEIYTHLT 325
            ..|||:|||||||:|.||||::.|:||||:|.|.||:|:|.:||:.:|..||.|:|.||||:|:|
Frog   256 ATTSIVLFLNKKDVFTEKIKKAHLSICFPDYDGPNTYEDAGSYIKTQFLELNMRRDVKEIYSHMT 320

  Fly   326 CATDTNNVKFVFDAVTDVIIKNNLKQIGLF 355
            |||||.|||||||||||:|||.|||..|||
Frog   321 CATDTENVKFVFDAVTDIIIKENLKDCGLF 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Galphai	NP_477502.1	G_alpha	14..353	CDD:214595	208/338 (62%)
Galphai	NP_477502.1	G-alpha	35..349	CDD:206639	201/313 (64%)
gnat1	NP_001096278.1	G-alpha	30..344	CDD:206639	201/313 (64%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D406662at33208
OrthoFinder	1	1.000	-	-		FOG0000052
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10218
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.030