DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9953 and AT4G36190

DIOPT Version :9

Sequence 1:	NP_648067.2	Gene:	CG9953 / 38763	FlyBaseID:	FBgn0035726	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	NP_567998.3	Gene:	AT4G36190 / 829776	AraportID:	AT4G36190	Length:	482	Species:	Arabidopsis thaliana

Alignment Length:	547	Identity:	161/547 - (29%)
Similarity:	242/547 - (44%)	Gaps:	125/547 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LGVGLL-----LLGLLAPISGMGFRRGRLTKGFLGEPSKIPTLQRSLHSEDLWFEQRLDHFKSSD 70
            ||..||     ||..|:..:|: .:..|::.| |.:.||.      |..::|||.|.|||:..||
plant     5 LGFALLTTFTVLLSYLSFSNGL-LQPRRISHG-LSKSSKY------LTRDELWFTQTLDHYSPSD 61

  Fly    71 KRTWQQRYFVNADFYRNDSSAPVFLMIGGEGEASAKWMREGAWVHY----AEHFGALCLQLEHRF 131
            .|.::|||:...|..| ....|:||||.|||..:      |...:|    |:.|.|..:.||||:
plant    62 HRKFRQRYYEYLDHLR-VPDGPIFLMICGEGPCN------GITNNYISVLAKKFDAGIVSLEHRY 119

  Fly   132 YGKSHPTADLSTENLHYLSSEQALEDLASF----VTAMKVKFNLGDG--QKWIAFGGSYPGSLAA 190
            ||||.|...|:|:||.||||:|||.|||:|    ..::.||||....  ..|..||.||.|:|:|
plant   120 YGKSSPFKSLATKNLKYLSSKQALSDLATFRQYYQDSLNVKFNRSSNVENPWFFFGVSYSGALSA 184

  Fly   191 WAREKYPELIYGSISSSGPLLAEVDFKEYFEVVKASLAAYKPECVDAVTRSFAQVEILLKHMIGQ 255
            |.|.|:|.|..||::||..:.|..:|.|:.:.:..|..   |||..|:..:...:|:.||  :..
plant   185 WFRLKFPHLTCGSLASSAVVRAVYEFPEFDQQIAESAG---PECETALQETNKLLELGLK--VNN 244

  Fly   256 RSLDEKFKTCTPIKDSIENDLDMANFFENLAGNFAGV--VQYNKDNSPHATITIDDICDVMLNT- 317
            |::...|       ::.|.|:| |:|...:|.  |||  :||...         |.:|..::..
plant   245 RAVKALF-------NATELDVD-ADFLYLIAD--AGVMAIQYGNP---------DKLCVPLVEAQ 290

  Fly   318 -TAGPPVTR---------LGLVNDMLLKESNTTCLDYKYDKMVADMKNVSWDSETAKGMRQWTYQ 372
             ..|..|..         :|:........|....||.......||              |.|.:|
plant   291 KNGGDLVEAYAKYVREFCMGVFGQSSKTYSRKHLLDTAVTLESAD--------------RLWWFQ 341

  Fly   373 TCHEFGFYQTSDNPADTFGDRFGVDFFIRQCMDVFSKNMNAKFLKLVVSATNDNYGALKPKTTNV 437
            .|.|..::|.:.........:...::.:..|..:|.|.:..:     |.|||..||:.|...|.:
plant   342 VCTEVAYFQVAPANDSIRSHQINTEYHLDLCKSLFGKGVYPE-----VDATNLYYGSDKIAATKI 401

  Fly   438 LYVHGSIDPW-HALGLVKSTNAA-LPT---------------------IYIEGTA-HCANMYEPV 478
            ::.:||.||| ||   .|.|::. ||:                     :.|||.| :|::
plant   402 IFTNGSQDPWRHA---SKQTSSPDLPSYIMTCHNCGHGSDLRGCPQSAMVIEGDAQNCSS----- 458

  Fly   479 KTDPPQLVAARNKILKFLAKLLDGYTS 505
                |..|   ||:.:.:.|.:|.:.|
plant   459 ----PDAV---NKVRQHMIKHIDLWLS 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9953	NP_648067.2	Peptidase_S28	61..492	CDD:253262	140/477 (29%)
AT4G36190	NP_567998.3	Abhydrolase	52..441	CDD:304388	132/441 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	149	1.000	Domainoid score	I1421
eggNOG	1	0.900	-	-		E1_KOG2182
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1623
OMA	1	1.010	-	-		QHG54248
OrthoDB	1	1.010	-	-		D555765at2759
OrthoFinder	1	1.000	-	-		FOG0001283
OrthoInspector	1	1.000	-	-		mtm1129
orthoMCL	1	0.900	-	-		OOG6_100644
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X417
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.740