DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9953 and CG11626

DIOPT Version :9

Sequence 1:	NP_648067.2	Gene:	CG9953 / 38763	FlyBaseID:	FBgn0035726	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	NP_001369023.1	Gene:	CG11626 / 42323	FlyBaseID:	FBgn0038705	Length:	486	Species:	Drosophila melanogaster

Alignment Length:	456	Identity:	139/456 - (30%)
Similarity:	219/456 - (48%)	Gaps:	32/456 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 EDLWFEQRLDHFKSSDKRTWQQRYFVNADFYRNDSSAPVFLMIGGEGEASAKWMREGAWVHYAEH 119
            |:||.:|::|||..::.|||:.||:.||.:::  ...|:::.:|||...|...:..|.....|..
  Fly    49 EELWLDQKVDHFDKNNNRTWKMRYYRNAKYFK--PHGPIYIFVGGEWTISPGLLSTGLTHDMAVE 111

  Fly   120 FGALCLQLEHRFYGKSHPTADLS--TENLHYLSSEQALEDLASFVTAMKVKFNLGDGQKWIAFGG 182
            ...:....|||:||.|.|..:.|  ..||..||..|:|.|||.|:...|......:..|.|..||
  Fly   112 NSGMLFYTEHRYYGLSLPFGNESYRLSNLKQLSLHQSLADLAHFIRHQKSNDPEMEDSKVILVGG 176

  Fly   183 SYPGSLAAWAREKYPELIYGSISSSGPLLAEVDFKEYFEVVKASL-AAYKPECVDAVTRSFAQVE 246
            ||.|||.||..:.||:||..|.:||.||||:.||.||.|:|..|: .:|...|...:.:.|   :
  Fly   177 SYSGSLVAWMTQLYPDLIAASWASSAPLLAKADFFEYMEMVGKSIQLSYGNNCSLRIEKGF---K 238

  Fly   247 ILLKHMIGQRSLDEKFKTCTPIKDSIENDLDMANFFENLAGNFAGVVQYNKDNSPHATITIDDIC 311
            .|:|...|....:..:.....:..|.:|.||.|.||..|...||.|||....:.|.       :|
  Fly   239 FLVKLFDGDEIQELLYNLNGCVGYSPKNPLDRAAFFNGLGNYFALVVQSYSASIPR-------LC 296

  Fly   312 DVMLNTTAGPPVTRLGLVNDMLLKES--NTTCLDYKYDKMVADMKNVSWDSETAKGMRQWTYQTC 374
            :.:::..:...:..:..:. :|..|.  ::.|.|:.|..|   ::..:.||..:...|.|.||||
  Fly   297 ETLMSLDSSDELAFIEFLK-LLYSEGRRSSDCQDFGYSSM---LELFTEDSVQSSETRAWFYQTC 357

  Fly   375 HEFGFYQTS---DNPADTFGDRFGVDFFIRQCMDVFSKNMNAKFLKLVVSATNDNYGAL----KP 432
            :|||:|.|:   .:.:..|.::..:.:|.:.|.|.|.....|..|...|..||..:|..    ..
  Fly   358 NEFGWYTTTKSKSSASQAFANQVPLGYFEQLCQDAFGAEQTAHQLAHGVEQTNSKFGGFGFNQSE 422

  Fly   433 KTTNVLYVHGSIDPWHALGLVKSTNAALPTIYIEGTAHCANMYEPVKTDPPQLVAARNKILKFLA 497
            :...|::.||.:|||.|||..|...|    |.:.|.:|..::......|..|:..|:.:::.||.
  Fly   423 RYAQVIFTHGELDPWSALGQQKGDQA----IVLTGYSHVEDLSSIRVMDSVQMNLAKLRVMSFLR 483

  Fly   498 K 498
            :
  Fly   484 R 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9953	NP_648067.2	Peptidase_S28	61..492	CDD:253262	134/442 (30%)
CG11626	NP_001369023.1	Abhydrolase	55..478	CDD:419691	134/442 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452027
Domainoid	1	1.000	149	1.000	Domainoid score	I1421
eggNOG	1	0.900	-	-		E1_KOG2182
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1623
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D297753at33208
OrthoFinder	1	1.000	-	-		FOG0001283
OrthoInspector	1	1.000	-	-		mtm1129
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11010
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X417
	10	9.900