DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9953 and CG3739

DIOPT Version :9

Sequence 1:	NP_648067.2	Gene:	CG9953 / 38763	FlyBaseID:	FBgn0035726	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	NP_650804.2	Gene:	CG3739 / 42320	FlyBaseID:	FBgn0038702	Length:	485	Species:	Drosophila melanogaster

Alignment Length:	509	Identity:	153/509 - (30%)
Similarity:	245/509 - (48%)	Gaps:	51/509 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LLLLGLLAPISGMGFRRGRLTKGFLGEPSK-----IPTLQRSLHS-------------EDLWFEQ 61
            |::|.||||::         ....|||...     :.:| |.||.             |:.|..|
  Fly     5 LVVLALLAPLT---------AAASLGEQKPEANAFVKSL-RELHRGPPVEPMKTRAKVEERWITQ 59

  Fly    62 RLDHFKSSDKRTWQQRYFVNADFYRNDSSAPVFLMIGGEGEASAKWMREGAWVHYA-EHFGALCL 125
            :||:|..|:..|||.|.::|..::.:.|  |:|:.:|||.......:..|.|...| :|.|:| |
  Fly    60 KLDNFDDSNNATWQDRIYINNKYFVDGS--PIFIYLGGEWAIDPSGITSGLWKDIAKQHNGSL-L 121

  Fly   126 QLEHRFYGKSHPTADLSTENL-HYLSSEQALEDLASFVTAMKVKFNLGDGQKWIAFGGSYPGSLA 189
            ..||||:|:|.|...|||||| .|.|.||||.|:.:.:..:|.:....| .|.:..|.||..::|
  Fly   122 YTEHRFFGQSIPITPLSTENLAKYQSVEQALADVINVIATLKQEDKYKD-SKVVVSGCSYSATMA 185

  Fly   190 AWAREKYPELIYGSISSSGPLLAEVDFKEYFEVVKASLAAYKPE-CVDAVTRSFAQVEILLKHMI 253
            .|.|:.|||:|.||.:||.||||:|:||:|.:||..|.|....: |.|.:..:.:..|.|.:...
  Fly   186 TWIRKLYPEIIRGSWASSAPLLAKVNFKDYMKVVGESYATLGGQYCYDLIDNATSYYENLFEIGN 250

  Fly   254 GQRSLDEKFKTCTPIKDSIENDLDMANFFENLAGNFAGVVQYNKDNSPHATITIDDICDVMLNTT 318
            |.:::.| ...|:..  ::.::.|....|..:|..|||:.||.|...    ..|...|.::...:
  Fly   251 GTQAVKE-LNLCSNF--NVNSEQDRWQIFSTIANIFAGIAQYQKPEK----YDIPTYCSILREFS 308

  Fly   319 AGPPVTRLGLVNDMLLKESNTTCLDYKYDKMVADMKNVSWDSETAKGM-RQWTYQTCHEFGFYQT 382
            ....|.....:| ..:.|.:..||...:...|.   ...|..|..:.. ..|.:|||.|||::|:
  Fly   309 DDDSVALSKFIN-WKINEHSGACLSTTFKGAVG---YYEWSKENYQDSDLPWIFQTCSEFGWFQS 369

  Fly   383 SDNPADTFGDRFGVDFFIRQCMDVFSKNMNAKFLKLVVSATNDNYGALKPKTTNVLYVHGSIDPW 447
            |.:.:..||..|....:...|..||....::..:...:.||||::|.|....||:.:|.|::|.|
  Fly   370 SGSRSQPFGSTFPATLYEDTCEGVFGAKYDSAGIHANIRATNDDFGGLNVNATNIYFVQGALDGW 434

  Fly   448 HALGLVKSTNAALPTIYIEGTAHCANMYEPVKTDPPQLVAARNKILKFLAKLLD 501
            ..:|...:..|.:    |...:||.:......:|..:|||::.|::|.:|:.|:
  Fly   435 SKVGAGVAQGATI----IPYASHCPDTGSISASDSAELVASKKKLIKLVAQWLE 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9953	NP_648067.2	Peptidase_S28	61..492	CDD:253262	134/434 (31%)
CG3739	NP_650804.2	Peptidase_S28	59..475	CDD:253262	134/434 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452025
Domainoid	1	1.000	149	1.000	Domainoid score	I1421
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1623
Isobase	1	0.950	-	0	Normalized mean entropy	S5466
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D297753at33208
OrthoFinder	1	1.000	-	-		FOG0001283
OrthoInspector	1	1.000	-	-		mtm1129
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11010
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X417
	10	9.950