DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9953 and Prcp

DIOPT Version :9

Sequence 1:	NP_648067.2	Gene:	CG9953 / 38763	FlyBaseID:	FBgn0035726	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	NP_001099751.2	Gene:	Prcp / 293118	RGDID:	1307842	Length:	493	Species:	Rattus norvegicus

Alignment Length:	536	Identity:	143/536 - (26%)
Similarity:	238/536 - (44%)	Gaps:	102/536 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 LLAPISGMGFR---RGRLTKGFLGEP--------SKIPTLQRSLHSEDLWFEQRLDHFKSSDKRT 73
            ||.|...:|..   |.||..  ||.|        ..:|: ..|:|    :|:|::|||..||.||
  Rat     7 LLLPFLSLGAATTIRPRLKT--LGSPHLSTNTPDPAVPS-SYSVH----YFQQKVDHFGFSDTRT 64

  Fly    74 WQQRYFVNADFYRNDSSAPVFLMIGGEGEASAKWMREGAWVHYAEHFGALCLQLEHRFYGKSHPT 138
            ::|||.| ||.:...:...:....|.||:........|.....||...|:.:..|||:||||.|.
  Rat    65 FKQRYLV-ADKHWQRNGGSILFYTGNEGDIVWFCNNTGFMWDVAEELKAMLVFAEHRYYGKSLPF 128

  Fly   139 ADLS---TENLHYLSSEQALEDLASFVTAMKVKFNLGDGQKWIAFGGSYPGSLAAWAREKYPELI 200
            ...|   :::|::|:|||||.|.|..:..:|......:||..||.||||.|.||||.|.|||.::
  Rat   129 GRDSFKDSQHLNFLTSEQALADFAELIRHLKETIPGTEGQPVIAIGGSYGGMLAAWFRMKYPHIV 193

  Fly   201 YGSISSSGPLLAEVD----FKEYFEVVKASLAAYKPECVDAVTRSFAQVEILLKHMIGQRSLDEK 261
            .|::::|.|:. ::|    ..|:.::|....:...|.|.:::.||::.:..|.....|.:.|.:.
  Rat   194 VGALAASAPIW-QLDGMAPCGEFMKIVTKDFSQSGPHCSESIRRSWSVINRLSDTGSGLQWLRDT 257

  Fly   262 FKTCTPIKDSIENDLD--MANFFENLAGNFAGVVQYNKDNSPHA--------TITIDDICDVMLN 316
            ...|:|:.......|.  :|..:.|||     :|.|     |:|        ...|.::|..:.|
  Rat   258 LHLCSPLTSEKMPTLKGWIAETWVNLA-----MVNY-----PYACNFLQPLPAWPIKEVCRYLRN 312

  Fly   317 TTAGPPVTRLGLVNDMLLKESNTTCLD--YKYDKMVADMKNVSWDSETAKGMRQWTYQTCHEFGF 379
            ..          |:|.:|.::....|:  |.|......: |:|..:.::.|...|::|.|.|...
  Rat   313 PN----------VSDTVLLQNIFQALNVYYNYSGQTKCL-NISQTTTSSLGSTGWSFQACTEMVM 366

  Fly   380 -YQTSDNPADTFGDRFGVDFFIRQCMDVFSKNMNAKFLKLVVSATND--NYGALKPK----TT-- 435
             :.|:           |:|       |:|.     .:|..:.:.:||  |...:||:    ||
  Rat   367 PFCTN-----------GID-------DMFE-----PYLWDLETYSNDCFNQWGVKPRPHWMTTMY 408

  Fly   436 ---------NVLYVHGSIDPWHALGLVKSTNAALPTIYIEGTAHCANMYEPVKTDPPQLVAARNK 491
                     |:::.:|.:|||...|:.|.....|..|.|...||..::......||..::.:|..
  Rat   409 GGKNISSHSNIIFSNGDLDPWSGGGVTKDITDTLVAINIPEGAHHLDLRAHNAFDPSSVLLSRLL 473

  Fly   492 ILKFLAK-LLDGYTSA 506
            .:|.:.| :.|.|:::
  Rat   474 EVKHMKKWIADFYSNS 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9953	NP_648067.2	Peptidase_S28	61..492	CDD:253262	125/467 (27%)
Prcp	NP_001099751.2	Abhydrolase	52..471	CDD:304388	124/464 (27%)
Prcp	NP_001099751.2	MhpC	101..>211	CDD:223669	44/110 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D555765at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920