DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mis12 and Mis12

DIOPT Version :9

Sequence 1:	NP_648066.1	Gene:	Mis12 / 38762	FlyBaseID:	FBgn0035725	Length:	181	Species:	Drosophila melanogaster
Sequence 2:	NP_001381976.1	Gene:	Mis12 / 501706	RGDID:	1564837	Length:	206	Species:	Rattus norvegicus

Alignment Length:	205	Identity:	51/205 - (24%)
Similarity:	92/205 - (44%)	Gaps:	30/205 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDFNSLAYDQKFFNFTAAQ-----LSAEREHI------VQDIIKKGIGQIID-KIKTPATAELLE 53
            |..:.:||:.:||.||...     ..|.::|:      |:.:|.|.:..|.| :|.:..|.:..|
  Rat     1 MSVDPMAYEAQFFGFTPQTCLLRIYIAFQDHLFEVMQAVEQVILKKLEGIPDCEISSIQTRKCTE 65

  Fly    54 AEKETVERRFQASASKGLKALRELDSKVFHVPPHVLHPEHMFVENQYTSEEEEQKTAR-LEELKA 117
            .....::.||.....|..:.:.:   .:..:||::|.||....|....|||:.|...: ::||:.
  Rat    66 KFLCFMKGRFDNLFGKMEQLILQ---SILQIPPNILLPEDKCQETNPFSEEKFQLLKQEIKELQE 127

  Fly   118 KYRENM----AMLAHLKIEEEKYAAMEDLIQ--KEIEMQDRVQ------RSCSSL--NITKLKQF 168
            ||:..:    |:||.|:.::...|.:.:.:.  .|:|...|.|      .|..||  |..||:..
  Rat   128 KYKVELCTEQALLAELEEQKTVKAKLRETLTFFDELENIGRYQGTSNFRESLVSLVQNCRKLQDI 192

  Fly   169 WNQVPLQIKK 178
            .:.|..:.|:
  Rat   193 RDNVEKESKR 202

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mis12	NP_648066.1	None
Mis12	NP_001381976.1	Mis12	8..140	CDD:399099	37/148 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_107894
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900