DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10064 and wds

DIOPT Version :9

Sequence 1:	NP_648065.1	Gene:	CG10064 / 38761	FlyBaseID:	FBgn0035724	Length:	742	Species:	Drosophila melanogaster
Sequence 2:	NP_001245503.1	Gene:	wds / 53428	FlyBaseID:	FBgn0040066	Length:	361	Species:	Drosophila melanogaster

Alignment Length:	306	Identity:	66/306 - (21%)
Similarity:	125/306 - (40%)	Gaps:	52/306 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   352 LNIK-TWVLKLLRTCHTKSVYCITFPKNYSGVFATSGKECIRIWSSGRKQELLRIMVYNFNCACV 415
            |::| .:.||.....|||:|..:.|..|...:.::|..:.|:||.:
  Fly    56 LSVKPNYTLKFTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGA------------------- 101

  Fly   416 RFTHDGTSIVSVWNDGIIRAFTPITGRLIYAIPNAHNKGCSALAVASSGRLIVTGGIEGQVRVWK 480
               :||....::                     :.|..|.|.:|.:|..||:|:|..:..::||:
  Fly   102 ---YDGKFEKTI---------------------SGHKLGISDVAWSSDSRLLVSGSDDKTLKVWE 142

  Fly   481 IDPYRQDLVGVLKDHSGPITSLDINYLDTEVISACTDGSCVIWDIKRMTRKQVVTANTQFMSASY 545
            :...:.  :..||.||..:...:.|.....::|...|.|..|||::.....:.:.|::..:||.:
  Fly   143 LSTGKS--LKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVSAVH 205

  Fly   546 F-PTGVQVITCGSDGRIIYWMVYNGALIRELTASKKSSVNCLAINETGDYFITVGSDLQVKLWDY 609
            | ..|..:::...||....|...:|..::.|.......|:.:..:..|.|.:....|..:|||||
  Fly   206 FNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDY 270

  Fly   610 NSGAVVGIGSEHASSVISCAYSPCMT----MFVTGSTDGSLIIWDV 651
            :.|..:...:.|.:... |.::....    ..|:||.|..:.||::
  Fly   271 SKGKCLKTYTGHKNEKY-CIFANFSVTGGKWIVSGSEDNMVYIWNL 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10064	NP_648065.1	WD40	<25..188	CDD:295369
		WD40	33..434	CDD:225201	16/82 (20%)
		WD40 repeat	65..106	CDD:293791
		WD40 repeat	111..151	CDD:293791
		WD40 repeat	159..186	CDD:293791
		WD40	280..652	CDD:225201	66/306 (22%)
		WD40	366..650	CDD:238121	61/288 (21%)
		WD40 repeat	370..407	CDD:293791	7/36 (19%)
		WD40 repeat	412..449	CDD:293791	2/36 (6%)
		WD40 repeat	456..494	CDD:293791	10/37 (27%)
		WD40 repeat	499..535	CDD:293791	7/35 (20%)
		WD40 repeat	541..576	CDD:293791	8/35 (23%)
		WD40 repeat	583..617	CDD:293791	10/33 (30%)
		WD40 repeat	625..651	CDD:293791	7/29 (24%)
wds	NP_001245503.1	WD40	64..358	CDD:238121	64/298 (21%)
		WD40 repeat	75..112	CDD:293791	9/79 (11%)
		WD40 repeat	118..154	CDD:293791	10/37 (27%)
		WD40 repeat	159..195	CDD:293791	7/35 (20%)
		WD40 repeat	202..237	CDD:293791	8/34 (24%)
		WD40 repeat	244..280	CDD:293791	10/35 (29%)
		WD40 repeat	288..325	CDD:293791	7/28 (25%)
		WD40 repeat	331..357	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0266
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810