DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10064 and WDR38

DIOPT Version :9

Sequence 1:NP_648065.1 Gene:CG10064 / 38761 FlyBaseID:FBgn0035724 Length:742 Species:Drosophila melanogaster
Sequence 2:NP_001263303.1 Gene:WDR38 / 401551 HGNCID:23745 Length:315 Species:Homo sapiens


Alignment Length:210 Identity:55/210 - (26%)
Similarity:95/210 - (45%) Gaps:22/210 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly   451 HNKGCSALAVASSGRLIVTGGIEGQVRVWKIDPYRQDLVGVLKDHSGPITSLDINYLDTEVISAC 515
            |....::.|.:..|::::||..:|.|..|  :.....|:..|..|:||:.....:.......||.
Human    20 HGGEVNSSAFSPDGQMLLTGSEDGCVYGW--ETRSGQLLWRLGGHTGPVKFCRFSPDGHLFASAS 82

  Fly   516 TDGSCVIWDIKRMTRKQVVTANTQFM-SASYFPTGVQVITCGSDGRIIYWMVYNGALIRELTASK 579
            .|.:..:||:.|....:|:..:.:.: :.|:.|...|:.:.|.|.|::.|.|.:|.::|.|...:
Human    83 CDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQMLRLLVGHR 147

  Fly   580 KS--------SVNCLAINETGDYFITVGSDLQVKLWDYN--SGAVVGIGSEHASSVISCAYSPCM 634
            .|        :|||||   ||.:      |..|.:||..  :.||.....|..|:.|||......
Human   148 DSIQSSDFSPTVNCLA---TGSW------DSTVHIWDLRMVTPAVSHQALEGHSANISCLCYSAS 203

  Fly   635 TMFVTGSTDGSLIIW 649
            .:..:||.|.::.||
Human   204 GLLASGSWDKTIHIW 218

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10064NP_648065.1 WD40 <25..188 CDD:295369
WD40 33..434 CDD:225201
WD40 repeat 65..106 CDD:293791
WD40 repeat 111..151 CDD:293791
WD40 repeat 159..186 CDD:293791
WD40 280..652 CDD:225201 55/210 (26%)
WD40 366..650 CDD:238121 55/210 (26%)
WD40 repeat 370..407 CDD:293791
WD40 repeat 412..449 CDD:293791
WD40 repeat 456..494 CDD:293791 9/37 (24%)
WD40 repeat 499..535 CDD:293791 7/35 (20%)
WD40 repeat 541..576 CDD:293791 10/35 (29%)
WD40 repeat 583..617 CDD:293791 13/35 (37%)
WD40 repeat 625..651 CDD:293791 8/25 (32%)
WDR38NP_001263303.1 WD40 <11..299 CDD:225201 55/210 (26%)
WD 1 19..58 9/39 (23%)
WD40 20..301 CDD:238121 55/210 (26%)
WD40 repeat 26..61 CDD:293791 9/36 (25%)
WD 2 61..100 9/38 (24%)
WD40 repeat 67..103 CDD:293791 7/35 (20%)
WD 3 103..142 9/38 (24%)
WD40 repeat 108..144 CDD:293791 10/35 (29%)
WD 4 145..184 13/47 (28%)
WD40 repeat 151..189 CDD:293791 13/46 (28%)
WD 5 190..228 9/29 (31%)
WD40 repeat 195..230 CDD:293791 8/24 (33%)
WD 6 231..272
WD40 repeat 236..272 CDD:293791
WD 7 275..313
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 295..315
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0266
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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