DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10064 and wdr-5.1

DIOPT Version :9

Sequence 1:NP_648065.1 Gene:CG10064 / 38761 FlyBaseID:FBgn0035724 Length:742 Species:Drosophila melanogaster
Sequence 2:NP_497749.1 Gene:wdr-5.1 / 175474 WormBaseID:WBGene00006474 Length:376 Species:Caenorhabditis elegans


Alignment Length:311 Identity:68/311 - (21%)
Similarity:121/311 - (38%) Gaps:37/311 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly   360 KLLRTC--HTKSVYCITFPK--NYSGVFATSGKECIRIWSSGRKQELLRIMVYNFNCACVRFTHD 420
            ||:.|.  ||||:....|..  .|.|  .:|..:.::||:.........:..:......:.::.|
 Worm    78 KLMCTLEGHTKSISSAKFSPCGKYLG--TSSADKTVKIWNMDHMICERTLTGHKLGVNDIAWSSD 140

  Fly   421 GTSIVSVWNDGIIRAFTPITGRLIYAIPNAHNKGCSALAVASSGRLIVTGGIEGQVRVWKIDPYR 485
            ...:||..:|..::.|..:|.|:...: ..||.............|:|:|..:..||:|  |...
 Worm   141 SRCVVSASDDKTLKIFEIVTSRMTKTL-KGHNNYVFCCNFNPQSSLVVSGSFDESVRIW--DVKT 202

  Fly   486 QDLVGVLKDHSGPITSLDINYLDTEVISACTDGSCVIWDIKRMTRKQVVTANTQFMS-------- 542
            ...:..|..||.|::::..|...:.:.|...||...|||          |||.|.:.        
 Worm   203 GMCIKTLPAHSDPVSAVSFNRDGSLIASGSYDGLVRIWD----------TANGQCIKTLVDDENP 257

  Fly   543 ----ASYFPTGVQVITCGSDGRIIYWMVYNGALIRELTASKKSSVNCLAIN--ETGDYFITVGS- 600
                ..:.|.|..::....|..:..|....|..:::.|..:.|.. |:..|  .||..:|..|| 
 Worm   258 PVAFVKFSPNGKYILASNLDSTLKLWDFSKGKTLKQYTGHENSKY-CIFANFSVTGGKWIISGSE 321

  Fly   601 DLQVKLWDYNSGAVVGIGSEHASSVISCAYSPCMTMFVTGS--TDGSLIIW 649
            |.::.:|:..:..:|.....|...|::....|...:..:|:  .|..:.||
 Worm   322 DCKIYIWNLQTREIVQCLEGHTQPVLASDCHPVQNIIASGALEPDNKIHIW 372

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10064NP_648065.1 WD40 <25..188 CDD:295369
WD40 33..434 CDD:225201 17/77 (22%)
WD40 repeat 65..106 CDD:293791
WD40 repeat 111..151 CDD:293791
WD40 repeat 159..186 CDD:293791
WD40 280..652 CDD:225201 68/311 (22%)
WD40 366..650 CDD:238121 65/303 (21%)
WD40 repeat 370..407 CDD:293791 6/38 (16%)
WD40 repeat 412..449 CDD:293791 7/36 (19%)
WD40 repeat 456..494 CDD:293791 8/37 (22%)
WD40 repeat 499..535 CDD:293791 7/35 (20%)
WD40 repeat 541..576 CDD:293791 5/46 (11%)
WD40 repeat 583..617 CDD:293791 10/36 (28%)
WD40 repeat 625..651 CDD:293791 6/27 (22%)
wdr-5.1NP_497749.1 WD40 <76..372 CDD:225201 66/309 (21%)
WD40 79..373 CDD:238121 67/310 (22%)
WD40 repeat 90..127 CDD:293791 6/38 (16%)
WD40 repeat 133..169 CDD:293791 7/36 (19%)
WD40 repeat 174..210 CDD:293791 7/37 (19%)
WD40 repeat 217..252 CDD:293791 11/44 (25%)
WD40 repeat 259..295 CDD:293791 5/35 (14%)
WD40 repeat 303..340 CDD:293791 10/36 (28%)
WD40 repeat 346..372 CDD:293791 4/25 (16%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0266
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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