Protein Alignment SLC22A25 and CG33233

DIOPT Version :9

• Sequence 1: XP_016873173.1
• Gene: SLC22A25 / 387601
• HGNCID: 32935
• Length: 577
• Species: Homo sapiens
• Sequence 2: NP_995978.2
• Gene: CG33233 / 2769005
• FlyBaseID: FBgn0053233
• Length: 489
• Species: Drosophila melanogaster
• Alignment Length: 520
• Identity: 104/520 - (20%)
• Similarity: 189/520 - (36%)
• Gaps: 163/520 - (31%)

Human   113 TEPCVDGWV-------YDQSSFPSTIVTKWDLVCESQPLNSVAKFLFMAGMMVGGNLYGHLSDRK 170
            ||....|::       :|.|....|::.           ||:     :.||:..|...|.|:||
  Fly    35 TESMTAGYLVVLTSCEFDTSPKEKTLLA-----------NSL-----LGGMVASGLFIGFLADR- 82

Human   171 PLSSPNHVSTDCDEGLEVPIAIHQHHVFWFGRKFVLRWSYLQLAIVG-----TCAAFAPTILVYC 230
                                         :|||||:|     ||:||     ..:|..|.:....
  Fly    83 -----------------------------YGRKFVIR-----LALVGALSFSVISALMPDLYSLS 113

Human   231 SLRFLAGAATFSIIVNTVLLIVEWITHQFCAMALTLTLCAASIGHITLGSLAFVIRDQCILQLVM 295
            .:|.:.|....::....|..:.|:  |......:|:.:|:.|.|      ||.:   .|.|..:.
  Fly   114 VIRIIVGTFLSAVASLQVGFLGEF--HAIKWRPITVAICSQSQG------LALI---YCPLVAMA 167

Human   296 SAP------------------CFVFFLFSRWLA--------ESARWLIINNKPEEGLKELRKAAH 334
            ..|                  ..:||:...|||        |:..:|:..|:|::.|..|:....
  Fly   168 ILPNNFNVDLSSSYNLRVWRFLMMFFMIPGWLALVGICLVPETPHFLMSVNRPDKALLALKWICR 232

Human   335 RNGMKNAE-DILTMEVLKSTMKQE--LEAAQKKHSLCELLRIPNICK-RIC-FLSFVRFASTIPF 394
            .|..|..: ||...|...||..||  .:....::.|  |...|::.| .|| ||.|..|.::|
  Fly   233 MNRKKWEDVDITLSEEKSSTNDQEGFWKTVWYEYKL--LFSKPHVFKFFICLFLIFGIFFTSI-- 293

Human   395 WGLTL------HLQHLGNN----------------------------------VFLLQTLFGAVT 419
             ||.:      ::.:.|:|                                  ..|:..::...|
  Fly   294 -GLGIWFPVIRNMDNSGSNRLCDLVNNNPTFINHEADDTNGTDSESPKCNDEMTNLIDPVYYGFT 357

Human   420 -----LLANCVAPWALNHMSRRLSQMLLMFLLATCLLAIIFVPQEMQTLRVVLATLGVGAASLGI 479
                 :||:.:..|    |:|:  .::.:.:|.:.:|.|.....:..|:.::...|.:....:.|
  Fly   358 YIGCFILASVLVHW----MTRK--YVIALHILISMILGISLNIMKQPTVVLIFFVLMMVLPGVLI 416

Human   480 TCSTAQENELIPSIIRGRATGITGNFANIGGALASLMMILSIYSRPLPWIIYGVFAILSGLVVLL 544
            ..:|:...:.:|..:||:|..:..:.|..||.|.|.|  :.::.|....:.:.:|.:...:.|:|
  Fly   417 PLATSVLVDCLPVNLRGKALCMVRSLARFGGVLGSTM--IGLFIRVTCDVTFNIFNLCLAICVVL 479

Human   545  544
              Fly   480  479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A25	XP_016873173.1	None
CG33233	NP_995978.2	MFS_1	22..451	CDD:284993	98/488 (20%)
		MFS	23..>208	CDD:119392	46/234 (20%)
		MFS	354..>482	CDD:304372	27/134 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153351
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840