DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sgl and plcd4a

DIOPT Version :9

Sequence 1:	NP_476980.1	Gene:	sgl / 38760	FlyBaseID:	FBgn0261445	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	XP_694028.4	Gene:	plcd4a / 565669	ZFINID:	ZDB-GENE-050208-654	Length:	761	Species:	Danio rerio

Alignment Length:	260	Identity:	52/260 - (20%)
Similarity:	83/260 - (31%)	Gaps:	74/260 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 RAAESIMHILRANQKPGIHYDILSNPEFLAEGTAINDLLNADRVLIGGEETPEGHQAVEKLSWIY 195
            |..|..|.|...::|.|..:...|          :.|:          |...||||:...||...
Zfish    45 RLQEDCMTIWYQSKKAGNAHSTFS----------VGDV----------EAVREGHQSEVLLSIAD 89

  Fly   196 EHWIPKQNILTTNTWSSELSKLAANAFLAQRISSINSLSAVCEATGA-------------DVSEV 247
            |  .|.....|.             .|..:|    .:|..|.|:|..             ::..:
Zfish    90 E--FPPDRCFTL-------------VFRGRR----GNLDLVAESTKEAQSWIKGIRKLIDNLENM 135

  Fly   248 ARAVGLDSRIGSKFLQASVGFGGSCFQKDILNLIYICENLNLPEVAAYWQQVIDMNEYQKRRFSQ 312
            .:...||..|...|.:|.....|....|::.:|:.:..              :||||:...|...
Zfish   136 GQREKLDQWICDWFKKADKNRDGRMNFKEVRDLLKMMN--------------VDMNEHHALRLFT 186

  Fly   313 KIIESLFNTVSDKRIAILGFAFKKNTGDTRETAAITVCQTLLEEGAALDIYDPK--VEPEQIIDD 375
            ....|...|:.|....:    |.|..  |:....:.|.|....:|..|.:.|.|  ::.||:.:|
Zfish   187 MADRSQSGTLEDDEFVL----FYKML--TQREDILRVFQEYSADGQKLTLKDLKDFLQEEQLHED 245

Fly 376 375
Zfish 246 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sgl	NP_476980.1	PLN02353	1..459	CDD:177986	52/260 (20%)
plcd4a	XP_694028.4	PH_PLC_delta	24..139	CDD:270169	24/132 (18%)
		PH	32..129	CDD:278594	24/122 (20%)
		EF-hand_7	149..205	CDD:290234	13/73 (18%)
		EF-hand_10	159..208	CDD:291454	12/66 (18%)
		PLN02228	212..753	CDD:177873	9/34 (26%)
		EF-hand_like	213..295	CDD:286375	9/33 (27%)
		PI-PLCc_GDPD_SF	295..599	CDD:301322
		C2_PLC_like	631..758	CDD:175974
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000